Gene Symbol | NR1H2 |
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Entrez Gene | 7376 |
Alt Symbol | LXR-b, LXRB, NER, NER-I, RIP15, UNR |
Species | Human |
Gene Type | protein-coding |
Description | nuclear receptor subfamily 1, group H, member 2 |
Other Description | LX receptor beta|liver X nuclear receptor beta|nuclear orphan receptor LXR-beta|nuclear receptor NER|oxysterols receptor LXR-beta|steroid hormone-nuclear receptor NER|ubiquitously-expressed nuclear receptor |
Swissprots | E7EWA6 A8K490 P55055 Q5I0Y1 Q12970 B4DNM6 |
Accessions | EAW71850 EAW71851 EAW71852 EAW71853 EAW71854 EAW71855 P55055 AB307697 BAH02288 AI252503 AK091535 BAG52378 AK290855 BAF83544 AK297978 BAG60288 AL598714 BC007790 AAH07790 BC033500 AAH33500 BC047750 AAH47750 BC074500 AAH74500 CA414979 CR456706 CAG32987 CR749648 CAH18442 DA053472 DQ890654 ABM81580 HQ692835 ADZ17346 U07132 AAA61783 U14534 AAA58594 NM_001256647 NP_001243576 NM_007121 NP_009052 |
Function | Nuclear receptor. Binds preferentially to double- stranded oligonucleotide direct repeats having the consensus half- site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8; DLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407}. |
Tissue Specificity | Ubiquitous. |
Human LXR beta full length protein - ab81924 from Abcam
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Human LXR beta full length protein - ab81919 from Abcam
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Human LXR beta peptide - ab45624 from Abcam
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Human LXR beta protein fragment - ab129036 from Abcam
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Human LXR beta protein fragment - ab81804 from Abcam
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Human LXR beta protein fragment - ab82029 from Abcam
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Rat LXR beta peptide - ab39817 from Abcam
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NR1H2 / LXR Beta Antibody Blocking Peptide - LS-E25777 from LifeSpan Bioscience
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NR1H2 / LXR Beta Antibody Blocking Peptide - LS-E30851 from LifeSpan Bioscience
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NR1H2 / LXR Beta Antibody Blocking Peptide - LS-E11828 from LifeSpan Bioscience
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NR1H2 / LXR Beta Antibody Blocking Peptide - LS-E14015 from LifeSpan Bioscience
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NR1H2 / LXR Beta Antibody Blocking Peptide - LS-E16661 from LifeSpan Bioscience
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NR1H2 / LXR Beta Antibody Blocking Peptide - LS-E16662 from LifeSpan Bioscience
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NR1H2 / LXR Beta Antibody Blocking Peptide - LS-E9621 from LifeSpan Bioscience
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LXR beta/NR1H2 Recombinant Protein - H00007376-P01 from Novus Biologicals
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LXR beta/NR1H2 Blocking Peptide - NBP1-76256PEP from Novus Biologicals
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NR1H2-Antibody-N-term-Blocking-Peptide - BP8526a from Abgent, a WuXi AppTec company
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LXR beta blocking peptide - GTX89661-PEP from GeneTex
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Recombinant Human LXR beta-BDL (OPAE00010) - OPAE00010 from Aviva Systems Biology
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NR1H2 Protein (OPPA02426) - OPPA02426 from Aviva Systems Biology
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Human Nuclear Receptor Subfamily Group H, Member 2 protein - orb81238 from Biorbyt
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NR1H2 Blocking Peptide - 33R-6119 from Fitzgerald
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LXR beta Peptide - AC21-0606-P from Abcore
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NR1H2 - H00007376-P01-10 from Acris Antibodies
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NR1H2 - H00007376-P01-25 from Acris Antibodies
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