NR1H2

Gene Symbol NR1H2
Entrez Gene 7376
Alt Symbol LXR-b, LXRB, NER, NER-I, RIP15, UNR
Species Human
Gene Type protein-coding
Description nuclear receptor subfamily 1, group H, member 2
Other Description LX receptor beta|liver X nuclear receptor beta|nuclear orphan receptor LXR-beta|nuclear receptor NER|oxysterols receptor LXR-beta|steroid hormone-nuclear receptor NER|ubiquitously-expressed nuclear receptor
Swissprots E7EWA6 A8K490 P55055 Q5I0Y1 Q12970 B4DNM6
Accessions EAW71850 EAW71851 EAW71852 EAW71853 EAW71854 EAW71855 P55055 AB307697 BAH02288 AI252503 AK091535 BAG52378 AK290855 BAF83544 AK297978 BAG60288 AL598714 BC007790 AAH07790 BC033500 AAH33500 BC047750 AAH47750 BC074500 AAH74500 CA414979 CR456706 CAG32987 CR749648 CAH18442 DA053472 DQ890654 ABM81580 HQ692835 ADZ17346 U07132 AAA61783 U14534 AAA58594 NM_001256647 NP_001243576 NM_007121 NP_009052
Function Nuclear receptor. Binds preferentially to double- stranded oligonucleotide direct repeats having the consensus half- site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8; DLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407}.
Tissue Specificity Ubiquitous.

LXR-β (D6M9D) Rabbit mAb - 13519 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D6M9D
Western blot analysis of extracts from various cell lines using LXR-β (D6M9D) Rabbit mAb.

LXRα/β (C-19) - sc-1201 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LXRα/β (C-19): sc-1201. Western blot analysis of LXRβ expression in non-transfected: sc-117752 (A) and human LXRβ transfected: sc-116107 (B) 293T whole cell lysates.

LXRα/β (H-144) - sc-13068 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LXRα/β (H-144): sc-13068. Western blot analysis of LXRα/β expression in mouse liver tissue extract.

LXRα/β (C-20) - sc-1591 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LXRα/β (C-20): sc-1591. Western blot analysis of LXRβ expression in non-transfected: sc-117752 (A) and human LXRβ transfected: sc-116107 (B) 293T whole cell lysates.

LXRα/β (R-20) - sc-1206 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LXRα/β (R-20): sc-1206. Western blot analysis of LXRβ expression in non-transfected: sc-117752 (A) and human LXRβ transfected: sc-117211 (B) 293T whole cell lysates.

LXRα/β (S-20) - sc-1000 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LXRα/β (S-20): sc-1000. Western blot analysis of LXRβ expression in non-transfected: sc-117752 (A) and human LXRβ transfected: sc-116107 (B) 293T whole cell lysates.

LXRβ (H-8) - sc-133221 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LXRβ (H-8): sc-133221. Western blot analysis of LXRβ expression in non-transfected: sc-117752 (A) and human LXRβ transfected: sc-112157 (B) 293T whole cell lysates.

LXRβ (M-20) - sc-1203 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LXRβ (M-20): sc-1203. Western blot analysis of LXRβ expression in non-transfected: sc-117752 (A) and human LXRβ transfected: sc-116107 (B) 293T whole cell lysates.

LXRβ (N-20) - sc-1001 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LXRβ (N-20): sc-1001. Western blot analysis of LXRβ expression in mouse liver tissue extract.

LXRβ (S-16) - sc-34343 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LXRβ (S-16): sc-34343. Western blot analysis of LXRβ expression in non-transfected: sc-117752 (A) and human LXRβ transfected: sc-116107 (B) 293T whole cell lysates.

Anti-LXR beta antibody - ab76983 from Abcam

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-LXR beta antibody (ab76983) at 5 µg/ml + IMR-32 cell lysate at 25 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-LXR beta antibody - ab28479 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-LXR beta antibody (ab28479) at 1/1000 dilutionLane 1 : Rat liver cell lysateLane 2 : Mouse liver cell lysateLane 3 : HeLa cell lysateLysates/proteins at 25 µg per lane.SecondaryHRP-conjugated anti-rabbit

Anti-LXR beta antibody - ab106473 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-LXR beta antibody (ab106473) at 1 µg/mlLane 2 : Anti-LXR beta antibody (ab106473) at 2 µg/mlLane 1 : Human Lung Tissue Lysate Lane 2 : Human Lung Tissue Lysate Lysates/proteins at 15 µg per lane.

Anti-LXR beta antibody - ab24361 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-LXR beta antibody (ab24361) at 1 µg/ml + Human Bone Marrow lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-LXR beta antibody - ab117881 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-LXR beta antibody (ab117881) at 1 µg/mlLane 1 : Liver (Human) Tissue Lysate - adult normal tissue (ab29889)Lane 2 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 3 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell LysateLane 4 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell LysateLane 5 : A549 (Human lung adenocarcinoma epithelial cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-LXR beta antibody - ab58089 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-LXR beta antibody - ab58092 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-LXR beta antibody - ChIP Grade - ab56237 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-LXR beta antibody - ChIP Grade (ab56237) at 1.25 µg/ml + Transfected 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-LXR beta antibody - N-terminal - ab155140 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-LXR beta antibody - N-terminal (ab155140) at 1/1000 dilution + A549 whole cell lysate at 30 µg

Anti-LXR beta antibody - N-terminal - ab167440 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-LXR beta antibody - N-terminal (ab167440) at 1 mg/ml + Rat thymus lysate at 10 µgSecondaryGoat anti-rabbit IgG HRP

Anti-NR1H2 / LXR Beta Antibody (aa2-15) IHC-plus™ - LS-B2998 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-NR1H2 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2998 concentration 3 ug/ml.

Anti-NR1H2 / LXR Beta Antibody (N-Terminus) - LS-C31809 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Transfected 293T Cell Lysate

Anti-NR1H2 / LXR Beta Antibody (aa227-276) - LS-C80743 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%.

Anti-NR1H2 / LXR Beta Antibody (aa323-372) - LS-C109804 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
NR1H2 antibody LS-C109804 Western blot of Transfected 293T cell lysate.

Anti-NR1H2 / LXR Beta Antibody (N-Terminus) - LS-C108533 from LifeSpan Bioscience

Prices $325.00, $890.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Western blot of LXR-B in human lung tissue lysate with LXR-B antibody at (A) 1 and (B) 2 ug/ml.
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