NR1H2

Gene Symbol NR1H2
Entrez Gene 7376
Alt Symbol LXR-b, LXRB, NER, NER-I, RIP15, UNR
Species Human
Gene Type protein-coding
Description nuclear receptor subfamily 1, group H, member 2
Other Description LX receptor beta|liver X nuclear receptor beta|nuclear orphan receptor LXR-beta|nuclear receptor NER|oxysterols receptor LXR-beta|steroid hormone-nuclear receptor NER|ubiquitously-expressed nuclear receptor
Swissprots E7EWA6 A8K490 P55055 Q5I0Y1 Q12970 B4DNM6
Accessions EAW71850 EAW71851 EAW71852 EAW71853 EAW71854 EAW71855 P55055 AB307697 BAH02288 AI252503 AK091535 BAG52378 AK290855 BAF83544 AK297978 BAG60288 AL598714 BC007790 AAH07790 BC033500 AAH33500 BC047750 AAH47750 BC074500 AAH74500 CA414979 CR456706 CAG32987 CR749648 CAH18442 DA053472 DQ890654 ABM81580 HQ692835 ADZ17346 U07132 AAA61783 U14534 AAA58594 NM_001256647 NP_001243576 NM_007121 NP_009052
Function Nuclear receptor. Binds preferentially to double- stranded oligonucleotide direct repeats having the consensus half- site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8; DLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407}.
Tissue Specificity Ubiquitous.

LXRβ siRNA (h) - sc-45316 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LXRβ shRNA Plasmid (h) - sc-45316-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LXRβ shRNA (h) Lentiviral Particles - sc-45316-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU018341 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15486 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15486 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03746 from Sigma-Aldrich

Category miRNA

NR1H2 siRNA (Human) - CRH5046 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

LXR beta/NR1H2 RNAi - H00007376-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human NR1H2 (NM_007121.5) - SHH354660 from Creative biogene

Category siRNA
Species Reactivities Human

NR1H2 shRNA Plasmid (Human) - CHH5046 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NR1H2 miRNA 3'UTR clone - MiUTR3H-03322 from Creative biogene

Species Reactivities Human
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