Gene Symbol | LMX1A |
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Entrez Gene | 4009 |
Alt Symbol | LMX1, LMX1.1 |
Species | Human |
Gene Type | protein-coding |
Description | LIM homeobox transcription factor 1, alpha |
Other Description | LIM homeobox transcription factor 1-alpha|LIM/homeobox protein 1.1 |
Swissprots | Q8TE11 Q0VDB5 B3KXP6 Q5VWG4 Q8TE12 |
Accessions | AAL82892 AAL82893 CAL40521 EAW90743 EAW90744 Q8TE12 AK122800 AK127724 BAG54558 BC066353 AAH66353 BC119743 AAI19744 BC119744 AAI19745 BC160062 AAI60062 BM678780 JF432394 ADZ15611 XM_011509538 XP_011507840 XM_011509539 XP_011507841 XM_011509540 XP_011507842 NM_001033507 NM_177399 NM_001174069 NP_001167540 NM_177398 NP_796372 |
Function | Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}. |
Tissue Specificity | Isoform 1 is expressed in many tissues. Not found in heart, liver, spleen and testis. Relatively highly expressed in fetal brain. Isoform LMX1A-4B is expressed in testis. {ECO:0000269|PubMed:12062816}. |
LMX1A (C-17) - sc-54273 from Santa Cruz Biotechnology
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LMX1A (G-17) - sc-54274 from Santa Cruz Biotechnology
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LMX1A (H-52) - sc-134990 from Santa Cruz Biotechnology
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Anti-LMX1A antibody - ab31006 from Abcam
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Anti-LMX1A antibody - ab139726 from Abcam
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Anti-LMX1A antibody - ab82833 from Abcam
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Anti-LMX1A antibody - ab84739 from Abcam
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Anti-LMX1A antibody - C-terminal - ab189967 from Abcam
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Anti-LMX1A Antibody (aa130-159) - LS-C98137 from LifeSpan Bioscience
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Anti-LMX1A Antibody (C-Terminus) IHC-plus⢠- LS-B8881 from LifeSpan Bioscience
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Anti-LMX1A Antibody (Internal, AP) - LS-C244929 from LifeSpan Bioscience
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Anti-LMX1A Antibody (aa244-293) - LS-C29677 from LifeSpan Bioscience
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Anti-LMX1A Antibody (aa301-350) - LS-C30915 from LifeSpan Bioscience
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Anti-LMX1A Antibody (Internal, APC) - LS-C244930 from LifeSpan Bioscience
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Anti-LMX1A Antibody (Internal, Biotin) - LS-C244931 from LifeSpan Bioscience
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Anti-LMX1A Antibody (Internal, FITC) - LS-C244932 from LifeSpan Bioscience
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Anti-LMX1A Antibody (Internal, PE) - LS-C244933 from LifeSpan Bioscience
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Anti-LMX1A Antibody (Internal, Azide-free, HRP) - LS-C247684 from LifeSpan Bioscience
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Anti-LMX1A Antibody (aa244-293) - LS-C31594 from LifeSpan Bioscience
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Anti-LMX1A Antibody (N-Terminus) - LS-C101404 from LifeSpan Bioscience
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Anti-LMX1A Antibody (Internal) - LS-C327763 from LifeSpan Bioscience
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Anti-LMX1A Antibody (aa251-300) - LS-C116097 from LifeSpan Bioscience
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LMX1A Antibody - NBP2-41193 from Novus Biologicals
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Rabbit Anti-LMX1A Polyclonal Antibody - bs-12386R from Bioss
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Rabbit Anti-LMX1A Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12386R-A350 from Bioss
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