Gene Symbol | LMX1A |
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Entrez Gene | 4009 |
Alt Symbol | LMX1, LMX1.1 |
Species | Human |
Gene Type | protein-coding |
Description | LIM homeobox transcription factor 1, alpha |
Other Description | LIM homeobox transcription factor 1-alpha|LIM/homeobox protein 1.1 |
Swissprots | Q8TE11 Q0VDB5 B3KXP6 Q5VWG4 Q8TE12 |
Accessions | AAL82892 AAL82893 CAL40521 EAW90743 EAW90744 Q8TE12 AK122800 AK127724 BAG54558 BC066353 AAH66353 BC119743 AAI19744 BC119744 AAI19745 BC160062 AAI60062 BM678780 JF432394 ADZ15611 XM_011509538 XP_011507840 XM_011509539 XP_011507841 XM_011509540 XP_011507842 NM_001033507 NM_177399 NM_001174069 NP_001167540 NM_177398 NP_796372 |
Function | Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}. |
Tissue Specificity | Isoform 1 is expressed in many tissues. Not found in heart, liver, spleen and testis. Relatively highly expressed in fetal brain. Isoform LMX1A-4B is expressed in testis. {ECO:0000269|PubMed:12062816}. |
Human LMX1A full length protein - ab114765 from Abcam
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Mouse LMX1A peptide - ab31005 from Abcam
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LMX1A Antibody Blocking Peptide - LS-E3129 from LifeSpan Bioscience
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LMX1A Antibody Blocking Peptide - LS-E11481 from LifeSpan Bioscience
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LMX1A Antibody Blocking Peptide - LS-E31355 from LifeSpan Bioscience
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LMX1A Antibody Blocking Peptide - LS-E11181 from LifeSpan Bioscience
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LMX1A Antibody Blocking Peptide - LS-E13604 from LifeSpan Bioscience
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LMX1A Antibody Blocking Peptide - LS-E13417 from LifeSpan Bioscience
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Recombinant Human LMX1A Protein - H00004009-P01 from Novus Biologicals
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LMX1A - H00004009-P01-10 from Acris Antibodies
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LMX1A - H00004009-P01-25 from Acris Antibodies
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LMX1A (C-term) Control Peptide - AP55529CP-N from Acris Antibodies
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LMX1A Peptide - 7087P from ProSci
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LMX1A fusion protein - ag6623 from Proteintech Group
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LMX1A fusion protein - ag5311 from Proteintech Group
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Recombinant Human LMX1A - LMX1A-29601TH from Creative Biomart
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Recombinant Human LIM homeobox transcription factor 1-alpha(LMX1A) - CSB-YP848414HU CSB-EP848414HU CSB-BP848414HU CSB-MP848414HU from Cusabio
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LMX1A Protein - NBP1-81303PEP from Novus Biologicals
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LMX1A-Blocking-Peptide-C-term - BP21429b from Abgent, a WuXi AppTec company
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LMX1A Peptide, Human - M34GP08780H from Creative Peptides
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LIM homeobox transcription factor 1-alpha (LMX1A), Recombinant Protein - MBS1411634 from MyBioSource
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