Gene Symbol | KCNK6 |
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Entrez Gene | 9424 |
Alt Symbol | K2p6.1, KCNK8, TOSS, TWIK-2, TWIK2 |
Species | Human |
Gene Type | protein-coding |
Description | potassium channel, two pore domain subfamily K, member 6 |
Other Description | K2P6.1 potassium channel|TWIK-originated similarity sequence|TWIK-originated sodium similarity sequence|inward rectifying potassium channel protein TWIK-2|potassium channel subfamily K member 6 |
Swissprots | Q9HB47 Q9Y257 |
Accessions | CAB70443 CAC15489 CAC39539 CAC39540 EAW56776 Q9Y257 AF117708 AAD24000 AF134149 AAD22980 AF281302 AAG10506 AF281303 AAG10507 AK022344 AK222545 BAD96265 AK315653 BAG38019 BC004367 AAH04367 DQ893422 ABM84348 DQ896740 ABM87739 EU978937 ACH86096 XM_011527526 XP_011525828 XM_011527527 XP_011525829 NM_004823 NP_004814 |
Function | Exhibits outward rectification in a physiological K(+) gradient and mild inward rectification in symmetrical K(+) conditions. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Widespread expression, detected in all tissues tested except for skeletal muscle. Strongest expression in placenta, pancreas, heart, colon and spleen, lower levels detected in peripheral blood leukocytes, lung, liver, kidney and thymus. Lowest expression detected in brain. |
TWIK-2 (H-6) - sc-376515 from Santa Cruz Biotechnology
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TWIK-2 (N-14) - sc-11485 from Santa Cruz Biotechnology
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TWIK-2 (H-55) - sc-366028 from Santa Cruz Biotechnology
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TWIK-2 (C-17) - sc-11488 from Santa Cruz Biotechnology
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TWIK-2 (P-19) - sc-11486 from Santa Cruz Biotechnology
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Anti-KCNK6 antibody - C-terminal - ab84208 from Abcam
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Anti-KCNK6 / TWIK-2 Antibody (aa263-292, AP) - LS-C236761 from LifeSpan Bioscience
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Anti-KCNK6 / TWIK-2 Antibody (aa263-292, APC) - LS-C236763 from LifeSpan Bioscience
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Anti-KCNK6 / TWIK-2 Antibody (aa263-292, Biotin) - LS-C236764 from LifeSpan Bioscience
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Anti-KCNK6 / TWIK-2 Antibody (aa263-292, FITC) - LS-C236765 from LifeSpan Bioscience
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Anti-KCNK6 / TWIK-2 Antibody (aa263-292, PE) - LS-C236766 from LifeSpan Bioscience
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Anti-KCNK6 / TWIK-2 Antibody (aa263-292) - LS-C322400 from LifeSpan Bioscience
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Anti-KCNK6 / TWIK-2 Antibody (aa263-292, Azide-free, HRP) - LS-C249309 from LifeSpan Bioscience
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Anti-KCNK6 / TWIK-2 Antibody (aa71-120) - LS-C110195 from LifeSpan Bioscience
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Anti-KCNK6 / TWIK-2 Antibody (aa263-292) - LS-C157846 from LifeSpan Bioscience
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Potassium channel subfamily K member 6 Antibody - NBP2-34063 from Novus Biologicals
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Potassium channel subfamily K member 6 Antibody - NBP1-30817 from Novus Biologicals
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Potassium channel subfamily K member 6 Antibody - NBP1-46742 from Novus Biologicals
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Anti-Potassium Channel TWIK-2 antibody produced in rabbit - P6735 from Sigma-Aldrich
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Anti-KCNK6 antibody produced in rabbit - SAB2106398 from Sigma-Aldrich
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KCNK6 antibody - N-terminal region (ARP36723_P050) - ARP36723_P050 from Aviva Systems Biology
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KCNK6-AntibodyC-term - AP19580b from Abgent, a WuXi AppTec company
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K2P61-Antibody - AG1129 from Abgent, a WuXi AppTec company
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KCNK6 antibody, N-term - GTX47461 from GeneTex
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KCNK6 Antibody - C-terminal region (OAAB15117) - OAAB15117 from Aviva Systems Biology
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