| Gene Symbol |
KCNK6
|
| Entrez Gene |
9424
|
| Alt Symbol |
K2p6.1, KCNK8, TOSS, TWIK-2, TWIK2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
potassium channel, two pore domain subfamily K, member 6
|
| Other Description |
K2P6.1 potassium channel|TWIK-originated similarity sequence|TWIK-originated sodium similarity sequence|inward rectifying potassium channel protein TWIK-2|potassium channel subfamily K member 6
|
| Swissprots |
Q9HB47 Q9Y257
|
| Accessions |
CAB70443 CAC15489 CAC39539 CAC39540 EAW56776 Q9Y257 AF117708 AAD24000 AF134149 AAD22980 AF281302 AAG10506 AF281303 AAG10507 AK022344 AK222545 BAD96265 AK315653 BAG38019 BC004367 AAH04367 DQ893422 ABM84348 DQ896740 ABM87739 EU978937 ACH86096 XM_011527526 XP_011525828 XM_011527527 XP_011525829 NM_004823 NP_004814
|
| Function |
Exhibits outward rectification in a physiological K(+) gradient and mild inward rectification in symmetrical K(+) conditions.
|
| Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Widespread expression, detected in all tissues tested except for skeletal muscle. Strongest expression in placenta, pancreas, heart, colon and spleen, lower levels detected in peripheral blood leukocytes, lung, liver, kidney and thymus. Lowest expression detected in brain.
|
![Western Blot: Potassium channel subfamily K member 6 Overexpression Lysate (Adult Normal) [NBL1-12187] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Potassium channel subfamily K member 6.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8124_Potassium%2520channel%2520subfamily%2520K%2520member%25206%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-12187-img0002.jpg)