JMJD7-PLA2G4B

Gene Symbol JMJD7-PLA2G4B
Entrez Gene 8681
Alt Symbol HsT16992, cPLA2-beta
Species Human
Gene Type protein-coding
Description JMJD7-PLA2G4B readthrough
Other Description JMJD7-PLA2G4B protein|jumonji domain containing 7-phospholipase A2, group IVB (cytosolic) read-through
Swissprots P0C869 B4DRT9 Q19KD5 Q19KD6
Accessions EAW92521 AA064721 AB209150 BAD92387 AF065215 AAC78836 AF065216 AF121908 AAD32135 BC013415 BC128426 BC172355 AAI72355 BI768993 BU688449 DA080158 DA096882 DA121536 DQ523799 ABF69195 DQ523800 ABF69196 NM_001198588 NP_001185517 NM_005090 NP_005081 NR_015346
Function Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position with a preference for arachidonoyl phospholipids. Has a much weaker activity than PLA2G4A. Isoform 3 has calcium-dependent activity against palmitoyl-arachidonyl-phosphatidylethanolamine and low level lysophospholipase activity but no activity against phosphatidylcholine. Isoform 5 does have activity against phosphatidylcholine. {ECO:0000269|PubMed:10085124, ECO:0000269|PubMed:10358058, ECO:0000269|PubMed:16617059}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:16617059}.
Tissue Specificity Widely expressed. Expressed at higher level in brain, heart, liver, cerebellum and pancreas. Isoform 3 is widely expressed. {ECO:0000269|PubMed:10085124, ECO:0000269|PubMed:10358058, ECO:0000269|PubMed:16617059}.
Top Pathways Long-term depression, Choline metabolism in cancer, Oxytocin signaling pathway, VEGF signaling pathway, Inflammatory mediator regulation of TRP channels

JMJD7-PLA2G4B CRISPR/Cas9 KO Plasmid (h) - sc-418409 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD7-PLA2G4B HDR Plasmid (h) - sc-418409-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD7-PLA2G4B Double Nickase Plasmid (h) - sc-418409-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD7-PLA2G4B Double Nickase Plasmid (h2) - sc-418409-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD7-PLA2G4B CRISPR Activation Plasmid (h) - sc-418409-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD7-PLA2G4B CRISPR Activation Plasmid (h2) - sc-418409-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD7-PLA2G4B Lentiviral Activation Particles (h) - sc-418409-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD7-PLA2G4B Lentiviral Activation Particles (h2) - sc-418409-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

group IVB sPLA 2 siRNA (h) - sc-90277 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

group IVB sPLA 2 shRNA Plasmid (h) - sc-90277-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

group IVB sPLA 2 shRNA (h) Lentiviral Particles - sc-90277-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PLA2G4B RNAi - H00008681-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU087201 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10871 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10871 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02476 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02476

shRNA set against Human PLA2G4B(NM_005090.3) - SHR119136 from Creative biogene

Category siRNA
Species Reactivities Human

JMJD7-PLA2G4B miRNA 3'UTR clone - MiUTR1H-07961 from Creative biogene

Species Reactivities Human
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