Gene Symbol | SLAMF1 |
---|---|
Entrez Gene | 6504 |
Alt Symbol | CD150, CDw150, SLAM |
Species | Human |
Gene Type | protein-coding |
Description | signaling lymphocytic activation molecule family member 1 |
Other Description | IPO-3|signaling lymphocytic activation molecule |
Swissprots | Q13291 Q9HBE8 Q5W172 |
Accessions | AAG10433 AAG10434 AAG17628 CAR96687 CAR96689 EAW52706 Q13291 AA825199 AK304237 BAG65106 AK311666 AK314244 BAG36911 AY040554 AAK77968 BC012602 AAH12602 BC067847 BC110349 BC132792 AAI32793 BC144498 BC144499 BC144500 DB133023 HQ258195 ADR82949 KF471075 AHF72732 U33017 AAA75380 XM_005245456 XP_005245513 XM_005245457 XP_005245514 XM_011509905 XP_011508207 NM_003037 NP_003028 NR_104399 NR_104400 NR_104401 |
Function | High-affinity self-ligand important in bidirectional T- cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. Note=Present on the surface of B-cells and T-cells. |
Tissue Specificity | Constitutively expressed on peripheral blood memory T-cells, T-cell clones, immature thymocytes and a proportion of B-cells, and is rapidly induced on naive T-cells after activation. |
Top Pathways | Measles |
Human SLAM / CD150 full length protein - ab131872 from Abcam
|
||||||||||
Human SLAM / CD150 protein fragment - ab139259 from Abcam
|
||||||||||
Human SLAM / CD150 protein fragment - ab151342 from Abcam
|
||||||||||
Human SLAM / CD150 protein fragment - ab125998 from Abcam
|
||||||||||
SLAMF1 / SLAM / CD150 Antibody Blocking Peptide - LS-E22884 from LifeSpan Bioscience
|
||||||||||
SLAMF1 / SLAM / CD150 Antibody Blocking Peptide - LS-E22883 from LifeSpan Bioscience
|
||||||||||
SLAMF1 / SLAM / CD150 Antibody Blocking Peptide - LS-E7413 from LifeSpan Bioscience
|
||||||||||
SLAMF1 / SLAM / CD150 Antibody Blocking Peptide - LS-E7163 from LifeSpan Bioscience
|
||||||||||
SLAMF1 / SLAM / CD150 Antibody Blocking Peptide - LS-E31098 from LifeSpan Bioscience
|
||||||||||
SLAM/CD150 Recombinant Protein - H00006504-P02 from Novus Biologicals
|
||||||||||
Recombinant Human SLAM/CD150 Protein - NBP2-22804 from Novus Biologicals
|
||||||||||
SLAM/CD150 Blocking Peptide - NBP1-76555PEP from Novus Biologicals
|
||||||||||
SLAM/CD150 Peptide - P1672 from Novus Biologicals
|
||||||||||
SLAM/CD150 Recombinant Protein - H00006504-G01 from Novus Biologicals
|
||||||||||
SLAMF1-Antibody-Y307-Blocking-Peptide - BP2864a from Abgent, a WuXi AppTec company
|
||||||||||
Phospho-SLAMF1Y281-Antibody-Blocking-peptide - BP3541a from Abgent, a WuXi AppTec company
|
||||||||||
Recombinant Human SLAM/CD150, CF - 164-SL-050 from R&D Systems
|
||||||||||
Human CD150 protein - orb191098 from Biorbyt
|
||||||||||
Human SLAM protein - orb49653 from Biorbyt
|
||||||||||
SLAMF1 protein (His tag) - 30R-2947 from Fitzgerald
|
||||||||||
Human SLAMF1 Protein - abx069093 from Abbexa
|
||||||||||
CD150 / SLAMF1 (21-237, His-tag) - AR50707PU-N from Acris Antibodies
|
||||||||||
CD150 / SLAMF1 (21-237, His-tag) - AR50707PU-S from Acris Antibodies
|
||||||||||
CD150 / SLAMF1 - H00006504-G01 from Acris Antibodies
|
||||||||||
CD150 / SLAMF1 - H00006504-P02 from Acris Antibodies
|