SLAMF1

Gene Symbol SLAMF1
Entrez Gene 6504
Alt Symbol CD150, CDw150, SLAM
Species Human
Gene Type protein-coding
Description signaling lymphocytic activation molecule family member 1
Other Description IPO-3|signaling lymphocytic activation molecule
Swissprots Q13291 Q9HBE8 Q5W172
Accessions AAG10433 AAG10434 AAG17628 CAR96687 CAR96689 EAW52706 Q13291 AA825199 AK304237 BAG65106 AK311666 AK314244 BAG36911 AY040554 AAK77968 BC012602 AAH12602 BC067847 BC110349 BC132792 AAI32793 BC144498 BC144499 BC144500 DB133023 HQ258195 ADR82949 KF471075 AHF72732 U33017 AAA75380 XM_005245456 XP_005245513 XM_005245457 XP_005245514 XM_011509905 XP_011508207 NM_003037 NP_003028 NR_104399 NR_104400 NR_104401
Function High-affinity self-ligand important in bidirectional T- cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
Subcellular Location Cell membrane; Single-pass type I membrane protein. Note=Present on the surface of B-cells and T-cells.
Tissue Specificity Constitutively expressed on peripheral blood memory T-cells, T-cell clones, immature thymocytes and a proportion of B-cells, and is rapidly induced on naive T-cells after activation.
Top Pathways Measles

SLAM CRISPR/Cas9 KO Plasmid (h) - sc-404289 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLAM HDR Plasmid (h) - sc-404289-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLAM Double Nickase Plasmid (h) - sc-404289-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLAM Double Nickase Plasmid (h2) - sc-404289-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLAM CRISPR Activation Plasmid (h) - sc-404289-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLAM CRISPR Activation Plasmid (h2) - sc-404289-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLAM Lentiviral Activation Particles (h) - sc-404289-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLAM Lentiviral Activation Particles (h2) - sc-404289-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLAM siRNA (h) - sc-42974 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SLAM shRNA Plasmid (h) - sc-42974-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SLAM shRNA (h) Lentiviral Particles - sc-42974-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU062101 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19390 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19390 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05448 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05448

SLAMF1 siRNA (Human) - CRH4399 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLAM/CD150 RNAi - H00006504-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

SLAMF1 - MBS8220980 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human SLAMF1 siRNA - orb264901 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLAMF1 shRNA Plasmid (Human) - CHH4399 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SLAMF1 miRNA 3'UTR clone - MiUTR3H-06020 from Creative biogene

Species Reactivities Human
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