Gene Symbol | ADIPOQ |
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Entrez Gene | 9370 |
Alt Symbol | ACDC, ACRP30, ADIPQTL1, ADPN, APM-1, APM1, GBP28 |
Species | Human |
Gene Type | protein-coding |
Description | adiponectin, C1Q and collagen domain containing |
Other Description | 30 kDa adipocyte complement-related protein|adipocyte complement-related 30 kDa protein|adiponectin|adipose most abundant gene transcript 1 protein|adipose specific collagen-like factor|gelatin-binding protein 28 |
Swissprots | Q58EX9 Q15848 |
Accessions | BAA86716 CAB52413 CAT82843 CBL63519 EAW78165 Q15848 AK291525 BAF84214 AK312868 BAG35720 AL832470 AX767959 CAE01099 BC054496 AAH54496 BC096308 AAH96308 BC096309 AAH96309 BC096310 AAH96310 BC096311 AAH96311 D45371 BAA08227 EU420013 ABZ10942 XM_011513324 XP_011511626 NM_001177800 NP_001171271 NM_004797 NP_004788 |
Function | Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. {ECO:0000269|PubMed:11479627}. |
Subcellular Location | Secreted. |
Tissue Specificity | Synthesized exclusively by adipocytes and secreted into plasma. |
Top Pathways | Adipocytokine signaling pathway, Type II diabetes mellitus, PPAR signaling pathway, Non-alcoholic fatty liver disease (NAFLD), AMPK signaling pathway |
Adiponectin Human ELISA Kit - ab99968 from Abcam
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Adiponectin Human ELISA Kit - ab108786 from Abcam
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Rabbit Adiponectin ELISA Kit (Sandwich ELISA) - LS-F5126 from LifeSpan Bioscience
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Bovine Adiponectin ELISA Kit (Sandwich ELISA) - LS-F6080 from LifeSpan Bioscience
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Chicken Adiponectin ELISA Kit (Sandwich ELISA) - LS-F6369 from LifeSpan Bioscience
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Human Adiponectin ELISA Kit (Sandwich ELISA) - LS-F2599 from LifeSpan Bioscience
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Mouse Adiponectin ELISA Kit (Sandwich ELISA) - LS-F2600 from LifeSpan Bioscience
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Rat Adiponectin ELISA Kit (Sandwich ELISA) - LS-F2979 from LifeSpan Bioscience
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Pig Adiponectin ELISA Kit (Sandwich ELISA) - LS-F5346 from LifeSpan Bioscience
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Human Adiponectin ELISA Kit (Sandwich ELISA) - LS-F5430 from LifeSpan Bioscience
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Rat Adiponectin ELISA Kit (Sandwich ELISA) - LS-F5431 from LifeSpan Bioscience
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Mouse Adiponectin ELISA Kit (Sandwich ELISA) - LS-F5432 from LifeSpan Bioscience
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Dog Adiponectin ELISA Kit (Sandwich ELISA) - LS-F6326 from LifeSpan Bioscience
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Human Adiponectin ELISA Kit (Sandwich ELISA) - LS-F25 from LifeSpan Bioscience
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Human Adiponectin ELISA Kit (Sandwich ELISA) - LS-F10042 from LifeSpan Bioscience
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Rat Adiponectin ELISA Kit (Sandwich ELISA) - LS-F10043 from LifeSpan Bioscience
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Mouse Adiponectin ELISA Kit (Sandwich ELISA) - LS-F10044 from LifeSpan Bioscience
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Hamster Adiponectin ELISA Kit (Sandwich ELISA) - LS-F10175 from LifeSpan Bioscience
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Dog Adiponectin ELISA Kit (Sandwich ELISA) - LS-F10753 from LifeSpan Bioscience
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Human Adiponectin ELISA Kit (Sandwich ELISA) - LS-F10752 from LifeSpan Bioscience
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ADIPOQ / Adiponectin EIA Kit - RAB0004 from Sigma-Aldrich
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Human ADIPOQ / Adiponectin ELISA Kit - RAB0005 from Sigma-Aldrich
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Adiponectin ELISA Kit - SE120138 from Sigma-Aldrich
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Adiponectin/CTRP1-7, Antibody Sampler Set, BioAssay - A0884-80M from USBiological Life Science |
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Human Adiponectin/Acrp30 Biotin Fluorokine Kit - NFADIP from R&D Systems
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