Gene Symbol | PDLIM7 |
---|---|
Entrez Gene | 9260 |
Alt Symbol | LMP1, LMP3 |
Species | Human |
Gene Type | protein-coding |
Description | PDZ and LIM domain 7 (enigma) |
Other Description | 1110003B01Rik|LIM domain protein|LMP|Lim mineralization protein 3|PDZ and LIM domain protein 7|protein enigma |
Swissprots | Q5XG82 Q9BXB8 Q9NR12 Q9BXB9 Q96C91 Q6NVZ5 Q14250 |
Accessions | AAC37565 EAW84985 EAW84986 EAW84987 EAW84988 Q9NR12 AF265209 AAF76152 AF345904 AAK30567 AF345905 AAK30568 AF345906 AAK30569 AK096826 BC001093 AAH01093 BC007648 BC014521 AAH14521 BC067806 BC084575 AAH84575 BG714861 BG772677 BU956109 CB993539 DQ892135 ABM83061 DQ895329 ABM86255 HY026171 XM_011534696 XP_011532998 XM_011534697 XP_011532999 XM_011534698 XP_011533000 XM_011534699 XP_011533001 XM_011534700 XP_011533002 NM_005451 NP_005442 NM_203352 NP_976227 NM_213636 NP_998801 NR_103804 NM_203353 |
Function | May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Colocalizes with RET to the cell periphery and in some cytoskeletal components. Colocalizes with TPM2 near the Z line in muscle. Colocalizes with TBX4 and TBX5 to actin filaments (By similarity). {ECO:0000250}. |
Tissue Specificity | Isoform 1 and isoform 2 are expressed ubiquitously, however, isoform 2 predominates in skeletal muscle, isoform 1 is more abundant in lung, spleen, leukocytes and fetal liver. {ECO:0000269|PubMed:11874232}. |
Enigma (D-10) - sc-376359 from Santa Cruz Biotechnology
|
||||||||||
Enigma (H-7) - sc-390330 from Santa Cruz Biotechnology
|
||||||||||
Enigma (H-12) - sc-398100 from Santa Cruz Biotechnology
|
||||||||||
Enigma (H-110) - sc-98370 from Santa Cruz Biotechnology
|
||||||||||
Enigma (A-20) - sc-70057 from Santa Cruz Biotechnology
|
||||||||||
Enigma (N-16) - sc-70060 from Santa Cruz Biotechnology
|
||||||||||
Enigma (L-14) - sc-70059 from Santa Cruz Biotechnology
|
||||||||||
Anti-PDLIM7 antibody - ab198259 from Abcam
|
||||||||||
Anti-PDLIM7 antibody - ab56504 from Abcam
|
||||||||||
Anti-PDLIM7 antibody [EPR13171] - ab182153 from Abcam
|
||||||||||
Anti-PDLIM7 antibody [EPR13171-104] - ab182161 from Abcam
|
||||||||||
Anti-PDLIM7 / LMP1 / Enigma Antibody (aa119-133) - LS-C147892 from LifeSpan Bioscience
|
||||||||||
Anti-PDLIM7 / Enigma Antibody (aa125-175) - LS-C288722 from LifeSpan Bioscience
|
||||||||||
Anti-PDLIM7 / Enigma Antibody (aa407-457) - LS-C288717 from LifeSpan Bioscience
|
||||||||||
Anti-PDLIM7 / LMP1 / Enigma Antibody (aa1-458, Azide-free) - LS-C330506 from LifeSpan Bioscience
|
||||||||||
Anti-PDLIM7 / Enigma Antibody (aa147-196) - LS-C201761 from LifeSpan Bioscience
|
||||||||||
Anti-PDLIM7 / Enigma Antibody - LS-C331050 from LifeSpan Bioscience
|
||||||||||
PDLIM7 Antibody (2D6) - H00009260-M01 from Novus Biologicals
|
||||||||||
PDLIM7 Antibody - NBP1-84841 from Novus Biologicals
|
||||||||||
LMP1 Antibody (S20-D) - NBP1-79009 from Novus Biologicals
|
||||||||||
PDLIM7 Antibody - H00009260-B01P from Novus Biologicals
|
||||||||||
PDLIM7 Antibody - NBP1-06533 from Novus Biologicals
|
||||||||||
PDLIM7 Antibody - NBP1-06534 from Novus Biologicals
|
||||||||||
PDLIM7 Antibody - H00009260-D01P from Novus Biologicals
|
||||||||||
Monoclonal Anti-PDLIM7 antibody produced in mouse - WH0009260M1 from Sigma-Aldrich
|