Gene Symbol | PDLIM7 |
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Entrez Gene | 9260 |
Alt Symbol | LMP1, LMP3 |
Species | Human |
Gene Type | protein-coding |
Description | PDZ and LIM domain 7 (enigma) |
Other Description | 1110003B01Rik|LIM domain protein|LMP|Lim mineralization protein 3|PDZ and LIM domain protein 7|protein enigma |
Swissprots | Q5XG82 Q9BXB8 Q9NR12 Q9BXB9 Q96C91 Q6NVZ5 Q14250 |
Accessions | AAC37565 EAW84985 EAW84986 EAW84987 EAW84988 Q9NR12 AF265209 AAF76152 AF345904 AAK30567 AF345905 AAK30568 AF345906 AAK30569 AK096826 BC001093 AAH01093 BC007648 BC014521 AAH14521 BC067806 BC084575 AAH84575 BG714861 BG772677 BU956109 CB993539 DQ892135 ABM83061 DQ895329 ABM86255 HY026171 XM_011534696 XP_011532998 XM_011534697 XP_011532999 XM_011534698 XP_011533000 XM_011534699 XP_011533001 XM_011534700 XP_011533002 NM_005451 NP_005442 NM_203352 NP_976227 NM_213636 NP_998801 NR_103804 NM_203353 |
Function | May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Colocalizes with RET to the cell periphery and in some cytoskeletal components. Colocalizes with TPM2 near the Z line in muscle. Colocalizes with TBX4 and TBX5 to actin filaments (By similarity). {ECO:0000250}. |
Tissue Specificity | Isoform 1 and isoform 2 are expressed ubiquitously, however, isoform 2 predominates in skeletal muscle, isoform 1 is more abundant in lung, spleen, leukocytes and fetal liver. {ECO:0000269|PubMed:11874232}. |
Human PDLIM7 full length protein - ab160403 from Abcam
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TRAF3 Antibody Blocking Peptide - LS-E2830 from LifeSpan Bioscience
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TRAF3 Antibody Blocking Peptide - LS-E30171 from LifeSpan Bioscience
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TRAF3 Antibody Blocking Peptide - LS-E30172 from LifeSpan Bioscience
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PDLIM7 Recombinant Protein - H00009260-P01 from Novus Biologicals
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PDLIM4/RIL blocking peptide - GTX26045-PEP from GeneTex
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E.coli LMP1 protein - orb246485 from Biorbyt
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PDLIM7 - H00009260-P01-02 from Acris Antibodies
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PDLIM7 fusion protein - ag1334 from Proteintech Group
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PDLIM7 fusion protein - Ag12274 from Proteintech Group
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PDLIM7,LMP1 fusion protein - ag0264 from Proteintech Group
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PDLIM7,LMP1 fusion protein - Ag4614 from Proteintech Group
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Recombinant Human PDLIM7, His-tagged - PDLIM7-1625H from Creative Biomart
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Recombinant Epstein-Barr virus (strain Raji) Latent membrane protein 1 - CSB-YP318333EFE CSB-BP318333EFE CSB-MP318333EFE from Cusabio
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Recombinant Epstein-Barr virus (strain Raji) Latent membrane protein 1 - CSB-EP318333EFE from Cusabio
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Recombinant Human PDZ and LIM domain protein 7(PDLIM7) - CSB-YP865112HU CSB-EP865112HU CSB-BP865112HU CSB-MP865112HU from Cusabio
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PDLIM7 (transcript variant 1) - TP301005 from Acris Antibodies
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PDLIM7 (transcript variant 2) - TP312656 from Acris Antibodies
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PDZ and LIM domain protein 7 (PDLIM7), Recombinant Protein - MBS1295050 from MyBioSource
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PDLIM7 Recombinant Protein Antigen - NBP1-84841PEP from Novus Biologicals
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PDLIM7 Peptide, Human - M34GP11547H from Creative Peptides
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LMP1 Recombinant Protein (OPCA01989) - OPCA01989 from Aviva Systems Biology
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LMP1 Recombinant Protein (OPCA02861) - OPCA02861 from Aviva Systems Biology
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LMP1 (156-164) peptide - orb70825 from Biorbyt
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Recombinant Epstein-Barr virus Latent membrane protein 1(LMP1),partial - CSB-YP314489EFC1 from Cusabio
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