PDLIM7

Gene Symbol PDLIM7
Entrez Gene 9260
Alt Symbol LMP1, LMP3
Species Human
Gene Type protein-coding
Description PDZ and LIM domain 7 (enigma)
Other Description 1110003B01Rik|LIM domain protein|LMP|Lim mineralization protein 3|PDZ and LIM domain protein 7|protein enigma
Swissprots Q5XG82 Q9BXB8 Q9NR12 Q9BXB9 Q96C91 Q6NVZ5 Q14250
Accessions AAC37565 EAW84985 EAW84986 EAW84987 EAW84988 Q9NR12 AF265209 AAF76152 AF345904 AAK30567 AF345905 AAK30568 AF345906 AAK30569 AK096826 BC001093 AAH01093 BC007648 BC014521 AAH14521 BC067806 BC084575 AAH84575 BG714861 BG772677 BU956109 CB993539 DQ892135 ABM83061 DQ895329 ABM86255 HY026171 XM_011534696 XP_011532998 XM_011534697 XP_011532999 XM_011534698 XP_011533000 XM_011534699 XP_011533001 XM_011534700 XP_011533002 NM_005451 NP_005442 NM_203352 NP_976227 NM_213636 NP_998801 NR_103804 NM_203353
Function May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Colocalizes with RET to the cell periphery and in some cytoskeletal components. Colocalizes with TPM2 near the Z line in muscle. Colocalizes with TBX4 and TBX5 to actin filaments (By similarity). {ECO:0000250}.
Tissue Specificity Isoform 1 and isoform 2 are expressed ubiquitously, however, isoform 2 predominates in skeletal muscle, isoform 1 is more abundant in lung, spleen, leukocytes and fetal liver. {ECO:0000269|PubMed:11874232}.

Enigma CRISPR/Cas9 KO Plasmid (h) - sc-403254 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Enigma HDR Plasmid (h) - sc-403254-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Enigma Double Nickase Plasmid (h) - sc-403254-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Enigma Double Nickase Plasmid (h2) - sc-403254-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Enigma CRISPR Activation Plasmid (h) - sc-403254-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Enigma CRISPR Activation Plasmid (h2) - sc-403254-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Enigma Lentiviral Activation Particles (h) - sc-403254-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Enigma Lentiviral Activation Particles (h2) - sc-403254-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Enigma siRNA (h) - sc-77273 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Enigma shRNA Plasmid (h) - sc-77273-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Enigma shRNA (h) Lentiviral Particles - sc-77273-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PDLIM7 RNAi - H00009260-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human
Western Blot: PDLIM7 RNAi [H00009260-R01V] - Analysis of PDLIM7 over-expressed 293 cell line, cotransfected with PDLIM7 Validated Chimera RNAi or non-transfected control. Blot probed with H00009260-M01. GAPDH (36.1 kDa) used as loading control.

PDLIM7 RNAi - H00009260-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

PDLIM7 RNAi - H00009260-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

PDLIM7 RNAi - H00009260-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

PDLIM7 RNAi - H00009260-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU134901 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16574 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

PDLIM7 siRNA (Human) - CRH6131 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PDLIM7 (NM_005451.3) - SHH372968 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PDLIM7(NM_005451.3) - SHR102696 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PDLIM7(NM_203352.1) - SHR102714 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PDLIM7(NM_213636.1) - SHR102732 from Creative biogene

Category siRNA
Species Reactivities Human

PDLIM7 shRNA Plasmid (Human) - CHH6131 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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