PURB

Gene Symbol	PURB
Entrez Gene	5814
Alt Symbol	PURBETA
Species	Human
Gene Type	protein-coding
Description	purine-rich element binding protein B
Other Description	purine-rich element-binding protein B|transcriptional activator protein Pur-beta
Swissprots	Q96QR8 A4D2L7
Accessions	AAS00366 EAL23749 EAW61073 Q96QR8 AA016115 AI042138 AI050971 AI209043 AI912557 AK054977 AK056651 AK057669 AL119133 AL705373 AY039216 AAK72462 BC101735 AAI01736 BC101737 AAI01738 BF964815 BG776957 BM015566 BQ890213 BU154650 BU177276 CB046374 DR005180 R89560 NM_033224 NP_150093
Function	Has capacity to bind repeated elements in single- stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine- rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:1448097}.
Tissue Specificity	Expressed in myocardium of heart failure patients. {ECO:0000269|PubMed:12933792}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Pur B full length protein - ab180276 from Abcam Category Protein Source E. coli Species Human

PURB Antibody Blocking Peptide - LS-E1394 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PURB Antibody Blocking Peptide - LS-E15073 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PURB-Antibody-C-term-Blocking-peptide - BP12051b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PURB Blocking Peptide - 33R-5621 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PURB protein (His tag) - 80R-3819 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

PURB (1-312, His-tag) - AR51506PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

PURB (1-312, His-tag) - AR51506PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

PURB, 1-312aa, Human, His tag, E.coli - 01-P2686 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

PURB fusion protein - Ag12705 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

PURB fusion protein - Ag12816 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human PURB, GST-tagged - PURB-2072H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Transcriptional activator protein Pur-beta(PURB) - CSB-YP847212HU CSB-EP847212HU CSB-BP847212HU CSB-MP847212HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PuRB, 1-312aa, Human, His tag, E.coli - ATGP2686 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

PURB Protein - NBP2-13829PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

Human PURB protein - orb260046 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

PURB Peptide, Human - M34GP12747H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Human PURB Protein - NBP2-51699 from Novus Biologicals Category Protein Prices $259.00, $759.00 Sizes 100 µg, 500 µg Source E.coli Species Human

PuRB - PAT-82685-1 from Nordic BioSite Category Protein Species Human

PuRB - PAT-82685-2 from Nordic BioSite Category Protein Species Human

PuRB, Recombinant Protein - MBS205607 from MyBioSource Category Protein Prices $310.00, $720.00 Sizes 100 µg, 500 µg Source E Coli Species Human

Purine-Rich Element Binding Protein B, Recombinant Protein - MBS145973 from MyBioSource Category Protein Prices $140.00, $205.00, $2,665.00 Sizes 5 µg, 20 µg, 1 mg

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