CCNY

Gene Symbol CCNY
Entrez Gene 219771
Alt Symbol C10orf9, CBCP1, CCNX, CFP1
Species Human
Gene Type protein-coding
Description cyclin Y
Other Description cyc-Y|cyclin box protein 1|cyclin fold protein 1|cyclin-X|cyclin-Y|cyclin-box carrying protein 1
Swissprots Q8TEX2 B7ZKX9 Q2M3V4 Q8TEX3 Q2TU96 Q96P45 Q96M99 Q7Z4U7 D3DRY9 Q8ND76 Q6NT86
Accessions EAW85912 EAW85913 EAW85914 Q8ND76 AA476431 AF413522 AAL07802 AF429969 AAP97301 AF465728 AAL78998 AF465729 AAL78999 AK024813 AK057280 BAB71409 AK303283 BAH13930 AK314666 BAG37223 AL834355 CAD39020 AY504868 AAS79427 BC015778 BC050310 BC069224 AAH69224 BC094815 AAH94815 BC104773 AAI04774 BC104801 AAI04802 BC143450 AAI43451 BC143455 AAI43456 BQ014589 BU159499 BU675909 DB037034 XM_005252388 XP_005252445 XM_006717392 XP_006717455 XM_011519357 XP_011517659 XM_011519358 XP_011517660 XM_011519359 XP_011517661 XM_011519360 XP_011517662 XM_011519361 XP_011517663 XM_011519362 XP_011517664 XM_011519363 XP_011517665 XM_011519364 XP_011517666 XM_011519365 XP_011517667 XM_011519366 XP_011517668 XM_011519367 XP_011517669 XM_011519368 XP_011517670 XM_011519369 XP_011517671 XM_011519370 XP_011517672 NM_001282852 NP_001269781 NM_001282853 NP_001269782 NM_001282854 NP_001269783 NM_145012 NP_659449 NM_181698 NP_859049
Function Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription. {ECO:0000269|PubMed:18060517, ECO:0000269|PubMed:19524571, ECO:0000269|PubMed:20059949, ECO:0000269|PubMed:22184064}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:18060517, ECO:0000269|PubMed:19524571, ECO:0000269|PubMed:20059949, ECO:0000269|PubMed:22184064}; Lipid-anchor {ECO:0000269|PubMed:18060517, ECO:0000269|PubMed:19524571, ECO:0000269|PubMed:20059949, ECO:0000269|PubMed:22184064}; Cytoplasmic side {ECO:0000269|PubMed:18060517, ECO:0000269|PubMed:19524571, ECO:0000269|PubMed:20059949, ECO:0000269|PubMed:22184064}.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:18060517}.

cyclin Y (S-19) - sc-242539 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
cyclin Y (S-19): sc-242539. Western blot analysis of cyclin Y expression in non-transfected: sc-117752 (A) and mouse cyclin Y transfected: sc-119552 (B) 293T whole cell lysates.

cyclin Y (N-20) - sc-242538 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
cyclin Y (N-20): sc-242538. Western blot analysis of cyclin Y expression in non-transfected: sc-117752 (A) and mouse cyclin Y transfected: sc-119552 (B) 293T whole cell lysates.

cyclin Y (L-19) - sc-242540 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
cyclin Y (L-19): sc-242540. Western blot analysis of cyclin Y expression in NIH/3T3 whole cell lysate.

Anti-Cyclin Y antibody - ab107012 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Cyclin Y antibody (ab107012) at 1/100 dilution + Mouse bladder tissue lysate at 35 µg

Anti-CCNY / Cyclin Y Antibody (aa147-177, APC) - LS-C233619 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNY / Cyclin Y Antibody (aa147-177, AP) - LS-C233618 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNY / Cyclin Y Antibody (aa147-177, Biotin) - LS-C233620 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNY / Cyclin Y Antibody (aa147-177, PE) - LS-C233622 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNY / Cyclin Y Antibody (aa147-177, FITC) - LS-C233621 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNY / Cyclin Y Antibody (aa147-177, Azide-free, HRP) - LS-C249623 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNY / Cyclin Y Antibody (aa147-177) - LS-C320130 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNY / Cyclin Y Antibody (aa146-195) - LS-C82529 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal liver lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-CCNY / Cyclin Y Antibody (aa140-169) - LS-C168485 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CCNY Antibody western blot of mouse bladder tissue lysates (35 ug/lane). The CCNY antibody detected the CCNY protein (arrow).

Anti-CCNY / Cyclin Y Antibody (clone 12F10) - LS-C340449 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 12F10
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CCNY (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CCNY (1:2000).

Anti-CCNY / Cyclin Y Antibody (aa291-441) - LS-C289128 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human Cyclin Y by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa (H), 293T (T), mouse NIH3T3 (3), and MCF7 (M) cells. Antibodies: Affinity purified rabbit anti-Cyclin Y antibody used for WB at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

CCNY Antibody - NBP1-58071 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CCNY Antibody [NBP1-58071] - Human Liver cell lysate, concentration 0.2-1 ug/ml.

CCNY Antibody - NBP1-88542 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: CCNY Antibody [NBP1-88542] - Staining of human gall bladder shows strong cytoplasmic and membranous positivity in glandular cells.

Cyclin Y/Cyclin X Polyclonal Antibody - bs-12060R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Cyclin Y/Cyclin X Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12060R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Cyclin Y/Cyclin X Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12060R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Cyclin Y/Cyclin X Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-12060R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Cyclin Y/Cyclin X Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-12060R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Cyclin Y/Cyclin X Polyclonal Antibody, Cy3 Conjugated - bs-12060R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Cyclin Y/Cyclin X Polyclonal Antibody, Cy5 Conjugated - bs-12060R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Cyclin Y/Cyclin X Polyclonal Antibody, Cy5.5 Conjugated - bs-12060R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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