PSMG2

Gene Symbol PSMG2
Entrez Gene 56984
Alt Symbol CLAST3, HCCA3, HsT1707, MDS003, PAC2, TNFSF5IP1
Species Human
Gene Type protein-coding
Description proteasome (prosome, macropain) assembly chaperone 2
Other Description CD40 ligand-activated specific transcript 3|HDCMC29P|HSPC260|PAC-2|hepatocellular carcinoma susceptibility protein|hepatocellular carcinoma-susceptibility protein 3|likely ortholog of mouse CD40 ligand-activated specific transcript 3 (Clast3)|proteasome assembling chaperone 2|proteasome assembly chaperone 2|tumor necrosis factor superfamily member 5-induced protein 1|tumor necrosis factor superfamily, member 5-induced protein 1|x 003 protein
Swissprots Q969U7 V9GYH7 B0YJB3 Q9NRV1 Q6IAH4
Accessions ACA06090 EAX01540 EAX01541 EAX01542 Q969U7 AF068295 AAF65184 AF161378 AAF28938 AF168712 AAF87314 AF276707 AAK69439 AK025410 AK057005 BAG51841 AK225882 BC013356 AAH13356 BF668035 BR000237 FAA00023 CR457181 CAG33462 HQ447389 ADQ31875 NM_020232 NP_064617 NM_147163 NP_671692
Function Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. {ECO:0000269|PubMed:16251969, ECO:0000269|PubMed:17707236}.
Subcellular Location Nucleus {ECO:0000250|UniProtKB:Q9EST4}.
Tissue Specificity Widely expressed with highest levels in lung, brain and colon. Moderately expressed in muscle, stomach, spleen and heart. Weakly expressed in small intestine, pancreas and liver. Highly expressed in hepatocellular carcinomas with low levels in surrounding liver tissue. {ECO:0000269|PubMed:11854909}.

Anti-PSMG2 antibody [EPR9947(2)] - ab172909 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9947(2)
All lanes : Anti-PSMG2 antibody [EPR9947(2)] (ab172909) at 1/1000 dilutionLane 1 : Caco-2 cell lysateLane 2 : HepG2 cell lysateLane 3 : HeLa cell lysateLane 4 : Jurkat cell lysate

Anti-TNFSF5IP1 / CLAST3 Antibody (clone 1E3) - LS-C340445 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E3
Immunocytochemistry staining of HT-29 cells using anti-PSMG2 mouse monoclonal antibody.(1:100).

Anti-TNFSF5IP1 / CLAST3 Antibody (aa217-246, AP) - LS-C217007 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNFSF5IP1 / CLAST3 Antibody (aa141-190) - LS-C186852 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Mouse Liver. Psmg2 antibody dilution 1.0 ug/ml.

Anti-TNFSF5IP1 / CLAST3 Antibody (aa217-246, APC) - LS-C217009 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNFSF5IP1 / CLAST3 Antibody (aa217-246, FITC) - LS-C217010 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNFSF5IP1 / CLAST3 Antibody (aa217-246, Biotin) - LS-C217011 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNFSF5IP1 / CLAST3 Antibody (aa217-246) - LS-C162253 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of PSMG2 Antibody in MDA-MB468 cell line lysates (35 ug/lane). PSMG2 (arrow) was detected using the purified antibody.

Anti-TNFSF5IP1 / CLAST3 Antibody (aa224-253) - LS-C324368 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNFSF5IP1 / CLAST3 Antibody (aa217-246, PE) - LS-C217013 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNFSF5IP1 / CLAST3 Antibody (aa217-246, Azide-free, HRP) - LS-C217012 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNFSF5IP1 / CLAST3 Antibody (clone 5H6) - LS-C340439 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5H6
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PSMG2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PSMG2 (1:2000).

Anti-TNFSF5IP1 / CLAST3 Antibody - LS-C192250 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of PSMG2 pAb in extracts from HEK-293T cells.

Anti-TNFSF5IP1 / CLAST3 Antibody - LS-C331059 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of 293T cell lysate using PSMG2 antibody.

Anti-TNFSF5IP1 / CLAST3 Antibody (C-Terminus) - LS-C345161 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of PSMG2 Antibody - C-terminal region with human HT1080 cells lysate.

PAC2 Antibody - NBP2-30576 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: PAC2 Antibody [NBP2-30576] - Staining of human kidney shows strong cytoplasmic and membranous positivity in cells in tubules.

PAC2 Antibody - NBP2-30574 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: PAC2 Antibody [NBP2-30574] - Immunofluorescent staining of human cell line U-251 MG shows localization to nuclear bodies.

PAC2 Antibody - H00056984-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: PAC2 Antibody [H00056984-B01] - analysis of TNFSF5IP1 expression in transfected 293T cell line by TNFSF5IP1 MaxPab polyclonal antibody. Lane 1: TNFSF5IP1 transfected lysate (29.04 KDa). Lane 2: Non-transfected lysate.

Anti-PSMG2 antibody produced in rabbit - HPA046741 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PSMG2: <B>Cat. No. HPA046741</B>: Immunohistochemical staining of human kidney shows strong luminal membranous positivity in renal tubules.

Anti-PSMG2 antibody produced in rabbit - HPA041517 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PSMG2: <B>Cat. No. HPA041517</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic and membranous positivity in cells in tubules.

ANTI-PSMG2 (C-TERM) antibody produced in rabbit - SAB1304506 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PSMG2 (56-70) antibody produced in rabbit - SAB1102509 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human PSMG2 was separated on SDS-PAGE, blotted with Anti-PSMG2 (56-70) (<B>Cat. No. SAB1102509</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:250

PSMG2 Antibody - C-terminal region (ARP67763_P050) - ARP67763_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PSMG2-Antibody-C-term - AP9698b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of PSMG2 Antibody (C-term) (Cat. #AP9698b) in MDA-MB468 cell line lysates (35ug/lane). PSMG2 (arrow) was detected using the purified Pab.

PSMG2 Antibody - C-terminal region (OAAB06295) - OAAB06295 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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