PSMG2

Gene Symbol PSMG2
Entrez Gene 56984
Alt Symbol CLAST3, HCCA3, HsT1707, MDS003, PAC2, TNFSF5IP1
Species Human
Gene Type protein-coding
Description proteasome (prosome, macropain) assembly chaperone 2
Other Description CD40 ligand-activated specific transcript 3|HDCMC29P|HSPC260|PAC-2|hepatocellular carcinoma susceptibility protein|hepatocellular carcinoma-susceptibility protein 3|likely ortholog of mouse CD40 ligand-activated specific transcript 3 (Clast3)|proteasome assembling chaperone 2|proteasome assembly chaperone 2|tumor necrosis factor superfamily member 5-induced protein 1|tumor necrosis factor superfamily, member 5-induced protein 1|x 003 protein
Swissprots Q969U7 V9GYH7 B0YJB3 Q9NRV1 Q6IAH4
Accessions ACA06090 EAX01540 EAX01541 EAX01542 Q969U7 AF068295 AAF65184 AF161378 AAF28938 AF168712 AAF87314 AF276707 AAK69439 AK025410 AK057005 BAG51841 AK225882 BC013356 AAH13356 BF668035 BR000237 FAA00023 CR457181 CAG33462 HQ447389 ADQ31875 NM_020232 NP_064617 NM_147163 NP_671692
Function Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. {ECO:0000269|PubMed:16251969, ECO:0000269|PubMed:17707236}.
Subcellular Location Nucleus {ECO:0000250|UniProtKB:Q9EST4}.
Tissue Specificity Widely expressed with highest levels in lung, brain and colon. Moderately expressed in muscle, stomach, spleen and heart. Weakly expressed in small intestine, pancreas and liver. Highly expressed in hepatocellular carcinomas with low levels in surrounding liver tissue. {ECO:0000269|PubMed:11854909}.

PAC2 CRISPR/Cas9 KO Plasmid (h) - sc-412742 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAC2 HDR Plasmid (h) - sc-412742-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAC2 Double Nickase Plasmid (h) - sc-412742-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAC2 Double Nickase Plasmid (h2) - sc-412742-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAC2 CRISPR Activation Plasmid (h) - sc-412742-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAC2 CRISPR Activation Plasmid (h2) - sc-412742-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAC2 Lentiviral Activation Particles (h) - sc-412742-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAC2 Lentiviral Activation Particles (h2) - sc-412742-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAC2 siRNA (h) - sc-76033 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PAC2 shRNA Plasmid (h) - sc-76033-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PAC2 shRNA (h) Lentiviral Particles - sc-76033-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU093091 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17634 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17634 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02769 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02769

PSMG2 siRNA (Human) - CRJ1270 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PSMG2 (NM_020232.4) - SHH385588 from Creative biogene

Category siRNA
Species Reactivities Human

Human PSMG2 siRNA - orb271771 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PSMG2 shRNA Plasmid (Human) - CHJ1270 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PSMG2 miRNA 3'UTR clone - MiUTR3H-10757 from Creative biogene

Species Reactivities Human
Search more