Gene Symbol | CST3 |
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Entrez Gene | 1471 |
Alt Symbol | ARMD11 |
Species | Human |
Gene Type | protein-coding |
Description | cystatin C |
Other Description | bA218C14.4 (cystatin C)|cystatin 3|cystatin-3|cystatin-C|gamma-trace|neuroendocrine basic polypeptide|post-gamma-globulin |
Swissprots | P01034 B2R5J9 D3DW42 Q6FGW9 |
Accessions | AAA52164 CAA36497 CAA43856 CAJ44947 CBF57600 EAX10137 EAX10138 P01034 AB587083 BAJ83816 AK312213 BAG35146 BC013083 AAH13083 BC110305 AAI10306 BF509512 BT006839 AAP35485 BX647523 CR541988 CAG46785 CR542018 CAG46815 DQ891439 ABM82365 EU176584 ABW03385 HY042866 X05607 CAA29096 NM_000099 NP_000090 NM_001288614 NP_001275543 |
Function | As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. |
Subcellular Location | Secreted {ECO:0000269|PubMed:20189825}. |
Tissue Specificity | Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland. {ECO:0000269|PubMed:15274116, ECO:0000269|PubMed:20189825}. |
Top Pathways | Salivary secretion |
CST3-Over-expression-Lysate - LY10271a from Abgent, a WuXi AppTec company
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CST3 293T Cell Transient Overexpression Lysate(Denatured) - H00001471-T01 from Acris Antibodies
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CST3 overexpression lysate - LY400040 from Acris Antibodies
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CST3 293 Cell Lysate - 400135 from ABBIOTEC
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Cystatin C Overexpression Lysate (Denatured) - H00001471-T01 from Novus Biologicals
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Cystatin C Overexpression Lysate (Native) - NBL1-09546 from Novus Biologicals
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cystatin C (h): 293T Lysate - sc-111929 from Santa Cruz Biotechnology
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cystatin C (h3): 293 Lysate - sc-170214 from Santa Cruz Biotechnology
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CST3 Over-expression Lysate Product - GWB-6F8C96 from Genway Biotech
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Human Cystatin C / CST3 HEK293 Cell Lysate (WB positive control) - 10439-HNAHL-300 from Sino Biological
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Human Cystatin C / CST3 HEK293 Cell Lysate (WB positive control) - 10439-H08HL-300 from Sino Biological
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Cystatin C Overexpression Lysate (Denatured) - H00001471-T03 from Novus Biologicals
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Cystatin C (Cystatin C) Pure recombinant antigen - orb196511 from Biorbyt
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Human Cystatin C Human Cells Transfected Lysate (positive control) (denatured) - orb172866 from Biorbyt
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Human Cystatin C Human Cells Transfected Lysate (positive control) (denatured) - orb232825 from Biorbyt
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Panoply™ Human CST3 Knockdown Stable Cell Line - CSC-DC003740 from Creative biogene
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