| Gene Symbol |
CST3
|
| Entrez Gene |
1471
|
| Alt Symbol |
ARMD11
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cystatin C
|
| Other Description |
bA218C14.4 (cystatin C)|cystatin 3|cystatin-3|cystatin-C|gamma-trace|neuroendocrine basic polypeptide|post-gamma-globulin
|
| Swissprots |
P01034 B2R5J9 D3DW42 Q6FGW9
|
| Accessions |
AAA52164 CAA36497 CAA43856 CAJ44947 CBF57600 EAX10137 EAX10138 P01034 AB587083 BAJ83816 AK312213 BAG35146 BC013083 AAH13083 BC110305 AAI10306 BF509512 BT006839 AAP35485 BX647523 CR541988 CAG46785 CR542018 CAG46815 DQ891439 ABM82365 EU176584 ABW03385 HY042866 X05607 CAA29096 NM_000099 NP_000090 NM_001288614 NP_001275543
|
| Function |
As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity.
|
| Subcellular Location |
Secreted {ECO:0000269|PubMed:20189825}.
|
| Tissue Specificity |
Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland. {ECO:0000269|PubMed:15274116, ECO:0000269|PubMed:20189825}.
|
| Top Pathways |
Salivary secretion
|