SMPD4

Gene Symbol SMPD4
Entrez Gene 55627
Alt Symbol NET13, NSMASE-3, NSMASE3
Species Human
Gene Type protein-coding
Description sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
Other Description SKNY protein|neutral sphingomyelinase 3|neutral sphingomyelinase III|sphingomyelin phosphodiesterase 4
Swissprots Q9NXE4 B4DWK7 B4DRB8 E7ESA2 Q9P2C9 B4E0L6 Q9H0M2 Q6ZT43 Q9NWL2 Q6FI76 B4DM23 E9PCE6 Q6P1P7 Q9NW20 B4DQ31
Accessions AAY14883 CCQ43567 EAW55597 EAW55598 EAW55599 EAW55600 EAW55601 Q9NXE4 AA232420 AB037839 BAA92656 AF052134 AI393912 AK000304 BAA91070 AK000763 BAA91368 AK001227 BAA91567 AK056501 AK126920 BAC86751 AK297257 BAG59735 AK298609 BAG60793 AK299185 BAG61230 AK301576 BAG63069 AK303427 BAG64478 AK303519 BAG64547 AL136737 CAB66671 BC040941 BC064947 AAH64947 CR533550 CAG38581 DA797873 DB137488 EU367941 ACA48221 XM_011511443 XP_011509745 XM_011511444 XP_011509746 XM_011511445 XP_011509747 NM_001171084 NM_001171083 NP_001164554 NM_017751 NP_060221 NM_017951 NP_060421 NR_033230 NR_033231 NR_033232
Function Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. {ECO:0000269|PubMed:16517606}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:16517606}; Single-pass membrane protein {ECO:0000269|PubMed:16517606}. Golgi apparatus membrane {ECO:0000269|PubMed:16517606}; Single-pass membrane protein {ECO:0000269|PubMed:16517606}.
Tissue Specificity Widely expressed, with highest levels in heart and skeletal muscle. {ECO:0000269|PubMed:16517606}.
Top Pathways Sphingolipid metabolism

Anti-SMPD4 antibody - ab188428 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human cerebellum tissue labeling SMPD4 with ab188428 at 1/10 dilution.

Anti-SMPD4 antibody - ab107760 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-SMPD4 antibody (ab107760) at 1/100 dilution + A2058 cell line lysates at 35 µg

Anti-SMPD4 antibody - ab133935 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-SMPD4 antibody (ab133935) at 1 µg/ml + Rat testis lysate

Anti-SMPD4 Antibody (aa80-108) - LS-C161321 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SMPD4 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skeletal muscle followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-SMPD4 Antibody (aa80-108, AP) - LS-C224101 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SMPD4 Antibody (aa80-108, APC) - LS-C224102 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SMPD4 Antibody (aa80-108, Biotin) - LS-C224103 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SMPD4 Antibody (aa80-108, FITC) - LS-C224104 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SMPD4 Antibody (aa80-108, PE) - LS-C224106 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SMPD4 Antibody (aa126-155) - LS-C325212 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SMPD4 Antibody (aa80-108, Azide-free, HRP) - LS-C224105 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SMPD4 Antibody (aa301-350) - LS-C151243 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SMPD4 antibody Western Blot of Rat Testis.

SMPD4 Antibody - NBP2-33567 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SMPD4 Antibody [NBP2-33567] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

SMPD4 Antibody - NBP2-33460 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: SMPD4 Antibody [NBP2-33460] - Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.

Anti-SMPD4 antibody produced in rabbit - HPA046279 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SMPD4: <B>Cat. No. HPA046279</B>: Immunohistochemical staining of Human cerebellum shows strong cytoplasmic positivity in Purkinje cells.

Anti-SMPD4 antibody produced in rabbit - HPA049426 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SMPD4: <B>Cat. No. HPA049426</B>: Immunohistochemical staining of Human small intestine shows strong cytoplasmic positivity in glandular cells.

ANTI-SMPD4 (N-TERM) antibody produced in rabbit - SAB1301501 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SMPD4 (N-term): <B>Cat. No. SAB1301501</B>: SMPD4 Antibody (N-term) western blot analysis in A2058 cell line lysates (35 μg/lane).

SMPD4 Antibody - N-terminal region (OAAB03304) - OAAB03304 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

SMPD4-Antibody-N-term - AP5904a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
SMPD4 Antibody (N-term) (Cat. #AP5904a) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the SMPD4 antibody detected the SMPD4 protein (arrow).

SMPD4 antibody - orb36188 from Biorbyt

Prices $187.00, $383.00
Sizes 80 μl (Trial size), 400 μl
Host Rabbit
Clonality Polyclonal
Western Blot of A2058 cell line lysates (35ug/lane) using SMPD4 antibody.

SMPD4 Antibody - abx032661 from Abbexa

Host Rabbit
Clonality Polyclonal

Rabbit Anti-Human SMPD4 (N-term) - 102-16617 from RayBiotech

Host Rabbit
SMPD4 Antibody (N-term) (Cat# 102-16617) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the SMPD4 antibody detected the SMPD4 protein (arrow).

SMPD4 antibody (N-term) - STJ49742 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal
Clone RB24190

SMPD4 antibody - 14959-1-AP from Proteintech Group

Host Rabbit
Clonality Polyclonal

SMPD4, Polyclonal Antibody - MBS6001179 from MyBioSource

Prices $550.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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