SMPD4

Gene Symbol SMPD4
Entrez Gene 55627
Alt Symbol NET13, NSMASE-3, NSMASE3
Species Human
Gene Type protein-coding
Description sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
Other Description SKNY protein|neutral sphingomyelinase 3|neutral sphingomyelinase III|sphingomyelin phosphodiesterase 4
Swissprots Q9NXE4 B4DWK7 B4DRB8 E7ESA2 Q9P2C9 B4E0L6 Q9H0M2 Q6ZT43 Q9NWL2 Q6FI76 B4DM23 E9PCE6 Q6P1P7 Q9NW20 B4DQ31
Accessions AAY14883 CCQ43567 EAW55597 EAW55598 EAW55599 EAW55600 EAW55601 Q9NXE4 AA232420 AB037839 BAA92656 AF052134 AI393912 AK000304 BAA91070 AK000763 BAA91368 AK001227 BAA91567 AK056501 AK126920 BAC86751 AK297257 BAG59735 AK298609 BAG60793 AK299185 BAG61230 AK301576 BAG63069 AK303427 BAG64478 AK303519 BAG64547 AL136737 CAB66671 BC040941 BC064947 AAH64947 CR533550 CAG38581 DA797873 DB137488 EU367941 ACA48221 XM_011511443 XP_011509745 XM_011511444 XP_011509746 XM_011511445 XP_011509747 NM_001171084 NM_001171083 NP_001164554 NM_017751 NP_060221 NM_017951 NP_060421 NR_033230 NR_033231 NR_033232
Function Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. {ECO:0000269|PubMed:16517606}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:16517606}; Single-pass membrane protein {ECO:0000269|PubMed:16517606}. Golgi apparatus membrane {ECO:0000269|PubMed:16517606}; Single-pass membrane protein {ECO:0000269|PubMed:16517606}.
Tissue Specificity Widely expressed, with highest levels in heart and skeletal muscle. {ECO:0000269|PubMed:16517606}.
Top Pathways Sphingolipid metabolism

N-SMase3 CRISPR/Cas9 KO Plasmid (h) - sc-412557 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-SMase3 HDR Plasmid (h) - sc-412557-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-SMase3 Double Nickase Plasmid (h) - sc-412557-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-SMase3 Double Nickase Plasmid (h2) - sc-412557-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-SMase3 CRISPR Activation Plasmid (h) - sc-412557-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-SMase3 CRISPR Activation Plasmid (h2) - sc-412557-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-SMase3 Lentiviral Activation Particles (h) - sc-412557-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-SMase3 Lentiviral Activation Particles (h2) - sc-412557-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-SMase3 siRNA (h) - sc-95034 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

N-SMase3 shRNA Plasmid (h) - sc-95034-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

N-SMase3 shRNA (h) Lentiviral Particles - sc-95034-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU113501 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® esiRNA - EHU116241 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19801 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19801 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08686 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08686

SMPD4 siRNA (Human) - CRJ0786 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SMPD4 - MBS829721 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human SMPD4 siRNA - orb271287 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SMPD4 shRNA Plasmid (Human) - CHJ0786 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SMPD4 miRNA 3'UTR clone - MiUTR3H-11236 from Creative biogene

Species Reactivities Human

SMPD4 miRNA 3'UTR clone - MiUTR3H-11237 from Creative biogene

Species Reactivities Human
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