SMPD4

Gene Symbol SMPD4
Entrez Gene 55627
Alt Symbol NET13, NSMASE-3, NSMASE3
Species Human
Gene Type protein-coding
Description sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
Other Description SKNY protein|neutral sphingomyelinase 3|neutral sphingomyelinase III|sphingomyelin phosphodiesterase 4
Swissprots Q9NXE4 B4DWK7 B4DRB8 E7ESA2 Q9P2C9 B4E0L6 Q9H0M2 Q6ZT43 Q9NWL2 Q6FI76 B4DM23 E9PCE6 Q6P1P7 Q9NW20 B4DQ31
Accessions AAY14883 CCQ43567 EAW55597 EAW55598 EAW55599 EAW55600 EAW55601 Q9NXE4 AA232420 AB037839 BAA92656 AF052134 AI393912 AK000304 BAA91070 AK000763 BAA91368 AK001227 BAA91567 AK056501 AK126920 BAC86751 AK297257 BAG59735 AK298609 BAG60793 AK299185 BAG61230 AK301576 BAG63069 AK303427 BAG64478 AK303519 BAG64547 AL136737 CAB66671 BC040941 BC064947 AAH64947 CR533550 CAG38581 DA797873 DB137488 EU367941 ACA48221 XM_011511443 XP_011509745 XM_011511444 XP_011509746 XM_011511445 XP_011509747 NM_001171084 NM_001171083 NP_001164554 NM_017751 NP_060221 NM_017951 NP_060421 NR_033230 NR_033231 NR_033232
Function Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. {ECO:0000269|PubMed:16517606}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:16517606}; Single-pass membrane protein {ECO:0000269|PubMed:16517606}. Golgi apparatus membrane {ECO:0000269|PubMed:16517606}; Single-pass membrane protein {ECO:0000269|PubMed:16517606}.
Tissue Specificity Widely expressed, with highest levels in heart and skeletal muscle. {ECO:0000269|PubMed:16517606}.
Top Pathways Sphingolipid metabolism

Human SMPD4 ORF Clone(NM_017751.4) - CDCR302323 from Creative Biomart

Species Human
Accession NM_017751.4

Human SMPD4 ORF Clone(NM_017751.4) - CDCR302324 from Creative Biomart

Species Human
Accession NM_017751.4

Human SMPD4 ORF Clone(NM_001171083.2) - CDCR356150 from Creative Biomart

Species Human
Accession NM_001171083.2

Human SMPD4 ORF Clone(NM_001171083.2) - CDCR356151 from Creative Biomart

Species Human
Accession NM_001171083.2

human SMPD4 ORF clone - CDCH083710 from Creative Biomart

Species Human
Accession NM_001171083

human SMPD4 ORF clone - CDCH083711 from Creative Biomart

Species Human
Accession NM_001171083

human SMPD4 ORF clone - CDCH083712 from Creative Biomart

Species Human
Accession NM_001171083

human SMPD4 ORF clone - CDCH083713 from Creative Biomart

Species Human
Accession NM_001171083

human SMPD4 ORF clone - CDCH083714 from Creative Biomart

Species Human
Accession NM_001171083

human SMPD4 ORF clone - CDCH083715 from Creative Biomart

Species Human
Accession NM_001171083

Human SMPD4 ORF Clone(NM_017751.4) - CDCR302323 from Creative biogene

Species Human

human SMPD4 ORF clone (NM_001171083.2) - CDCH083714 from Creative biogene

Species Human
Search more