Gene Symbol | A4GALT |
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Entrez Gene | 53947 |
Alt Symbol | A14GALT, A4GALT1, Gb3S, P(k), P1, P1PK, PK |
Species | Human |
Gene Type | protein-coding |
Description | alpha 1,4-galactosyltransferase |
Other Description | CD77 synthase|GB3 synthase|P blood group (P one antigen)|P(k) antigen synthase|P1/Pk synthase|UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase|alpha-1,4-N-acetylglucosaminyltransferase|alpha4Gal-T1|globotriaosylceramide synthase|lactosylceramide 4-alpha-galactosyltransferase |
Swissprots | Q9NPC4 B2R7C4 Q9P1X5 |
Accessions | AAO39149 AAO39150 AAO39151 AAO39152 AAP47164 AAP47165 AAP47166 AAP47167 AAP47168 AAP47169 AAP47170 AAQ68076 AAS77212 AAS77213 AAS77214 AAS77215 AAS77216 AAS77217 AAS77218 AAS77219 AAS77220 AAS77221 AAX20109 ABP35532 ABP35533 ABQ10740 ABQ10741 AFM54542 AGF29465 BAA94503 CAC69260 CCB78515 CCH64301 CCH64302 CCH64303 CCH64304 EAW73274 Q9NPC4 AB037883 BAA95915 AJ245581 CAB93532 AK074388 AK130208 AK312927 BAG35771 BC017068 AAH17068 BC055286 AAH55286 CB150578 DQ891619 ABM82545 DQ894811 ABM85737 GU902275 GU902276 GU902277 XM_005261643 XP_005261700 XM_005261644 XP_005261701 XM_005261646 XP_005261703 XM_005261647 XP_005261704 XM_005261648 XP_005261705 XM_006724265 XP_006724328 XM_006724266 XP_006724329 XM_011530233 XP_011528535 XM_011530234 XP_011528536 NM_017436 NP_059132 |
Function | Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins. |
Subcellular Location | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | Ubiquitous. Highly expressed in kidney, heart, spleen, liver, testis and placenta. |
Top Pathways | Glycosphingolipid biosynthesis - globo series |
Human A4GALT full length protein - ab132210 from Abcam
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Human A4GALT protein fragment - ab125994 from Abcam
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A4GALT Antibody Blocking Peptide - LS-E55 from LifeSpan Bioscience
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A4GALT Antibody Blocking Peptide - LS-E17151 from LifeSpan Bioscience
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A4GALT Antibody Blocking Peptide - LS-E17150 from LifeSpan Bioscience
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Recombinant Human CD77 Synthase Protein - H00053947-Q01 from Novus Biologicals
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CD77 Synthase Recombinant Protein - H00053947-P01 from Novus Biologicals
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A4GALT-Antibody-N-term-Blocking-peptide - BP10116a from Abgent, a WuXi AppTec company
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alpha-1,4-N-acetylglucosaminyltransferase protein - orb197658 from Biorbyt
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A4GALT Blocking Peptide - 33R-9678 from Fitzgerald
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A4GALT Blocking Peptide - 33R-7959 from Fitzgerald
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CD77 Synthase / A4GALT - H00053947-Q01-10 from Acris Antibodies
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CD77 Synthase / A4GALT - H00053947-Q01-25 from Acris Antibodies
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A4GALT fusion protein - Ag3069 from Proteintech Group
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Recombinant Human A4GALT, GST-tagged - A4GALT-9186H from Creative Biomart
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Recombinant Gorilla gorilla gorilla Lactosylceramide 4-alpha-galactosyltransferase(A4GALT) - CSB-YP889022GGZ CSB-EP889022GGZ CSB-BP889022GGZ CSB-MP889022GGZ from Cusabio
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Recombinant Pongo pygmaeus Lactosylceramide 4-alpha-galactosyltransferase(A4GALT) - CSB-YP873565EXP CSB-EP873565EXP CSB-BP873565EXP CSB-MP873565EXP from Cusabio
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Recombinant Human Lactosylceramide 4-alpha-galactosyltransferase(A4GALT) - CSB-YP868276HU CSB-EP868276HU CSB-BP868276HU CSB-MP868276HU from Cusabio
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Recombinant Pan troglodytes Lactosylceramide 4-alpha-galactosyltransferase(A4GA - CSB-YP865049EQV CSB-EP865049EQV CSB-BP865049EQV CSB-MP865049EQV from Cusabio
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Recombinant Alpha-1,4-Galactosyltransferase (a4GALT) - RPC274Hu01 from Uscn Life Science Inc.
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Recombinant Alpha-1,4-Galactosyltransferase (a4GALT) - RPC274Mu01 from Uscn Life Science Inc.
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Recombinant Alpha-1,4-Galactosyltransferase (a4GALT) - RPC274Ra01 from Uscn Life Science Inc.
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Recombinant Human A4GALT protein, GST-tagged - A4GALT-9187H from Creative Biomart
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Recombinant Alpha-1,4-Galactosyltransferase (a4GALT) - RPC274Hu01 from Cloud-clone
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A4GALT Peptide, Human - M34GP00004H from Creative Peptides
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