Gene Symbol | A4GALT |
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Entrez Gene | 53947 |
Alt Symbol | A14GALT, A4GALT1, Gb3S, P(k), P1, P1PK, PK |
Species | Human |
Gene Type | protein-coding |
Description | alpha 1,4-galactosyltransferase |
Other Description | CD77 synthase|GB3 synthase|P blood group (P one antigen)|P(k) antigen synthase|P1/Pk synthase|UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase|alpha-1,4-N-acetylglucosaminyltransferase|alpha4Gal-T1|globotriaosylceramide synthase|lactosylceramide 4-alpha-galactosyltransferase |
Swissprots | Q9NPC4 B2R7C4 Q9P1X5 |
Accessions | AAO39149 AAO39150 AAO39151 AAO39152 AAP47164 AAP47165 AAP47166 AAP47167 AAP47168 AAP47169 AAP47170 AAQ68076 AAS77212 AAS77213 AAS77214 AAS77215 AAS77216 AAS77217 AAS77218 AAS77219 AAS77220 AAS77221 AAX20109 ABP35532 ABP35533 ABQ10740 ABQ10741 AFM54542 AGF29465 BAA94503 CAC69260 CCB78515 CCH64301 CCH64302 CCH64303 CCH64304 EAW73274 Q9NPC4 AB037883 BAA95915 AJ245581 CAB93532 AK074388 AK130208 AK312927 BAG35771 BC017068 AAH17068 BC055286 AAH55286 CB150578 DQ891619 ABM82545 DQ894811 ABM85737 GU902275 GU902276 GU902277 XM_005261643 XP_005261700 XM_005261644 XP_005261701 XM_005261646 XP_005261703 XM_005261647 XP_005261704 XM_005261648 XP_005261705 XM_006724265 XP_006724328 XM_006724266 XP_006724329 XM_011530233 XP_011528535 XM_011530234 XP_011528536 NM_017436 NP_059132 |
Function | Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins. |
Subcellular Location | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | Ubiquitous. Highly expressed in kidney, heart, spleen, liver, testis and placenta. |
Top Pathways | Glycosphingolipid biosynthesis - globo series |
CD77 synthase (W-18) - sc-27697 from Santa Cruz Biotechnology
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CD77 synthase (T-20) - sc-27698 from Santa Cruz Biotechnology
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CD77 synthase (H-160) - sc-32950 from Santa Cruz Biotechnology
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Anti-A4GALT antibody - ab203681 from Abcam
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Anti-A4GALT antibody - ab101552 from Abcam
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Anti-A4GALT antibody - ab98998 from Abcam
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Anti-A4GALT Antibody (aa26-54, APC) - LS-C232269 from LifeSpan Bioscience
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Anti-A4GALT Antibody (aa26-54, AP) - LS-C232268 from LifeSpan Bioscience
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Anti-A4GALT Antibody (aa26-54, Biotin) - LS-C232270 from LifeSpan Bioscience
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Anti-A4GALT Antibody (aa26-54, FITC) - LS-C232271 from LifeSpan Bioscience
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Anti-A4GALT Antibody (aa26-54, Azide-free, HRP) - LS-C249346 from LifeSpan Bioscience
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Anti-A4GALT Antibody (aa26-54, PE) - LS-C232273 from LifeSpan Bioscience
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Anti-A4GALT Antibody (aa33-62) - LS-C319229 from LifeSpan Bioscience
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Anti-A4GALT Antibody (aa179-228) - LS-C108003 from LifeSpan Bioscience
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Anti-A4GALT Antibody (aa26-54) - LS-C155824 from LifeSpan Bioscience
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Anti-A4GALT Antibody (aa254-354) - LS-C306007 from LifeSpan Bioscience
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Anti-A4GALT Antibody (aa215-264) - LS-C108004 from LifeSpan Bioscience
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CD77 Synthase Antibody - NBP1-62583 from Novus Biologicals
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CD77 Synthase Antibody - NBP1-90824 from Novus Biologicals
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CD77 Synthase Antibody - NBP1-69594 from Novus Biologicals
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CD77 Synthase Antibody (3E12) - H00053947-M08 from Novus Biologicals
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CD77 Synthase Antibody (3E12) - H00053947-M08A from Novus Biologicals
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A4GALT Polyclonal Antibody - bs-7588R from Bioss
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Monoclonal Anti-A4GALT, (C-terminal) antibody produced in mouse - SAB1405116 from Sigma-Aldrich
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Monoclonal Anti-A4GALT antibody produced in mouse - WH0053947M8 from Sigma-Aldrich
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