A4GALT

Gene Symbol A4GALT
Entrez Gene 53947
Alt Symbol A14GALT, A4GALT1, Gb3S, P(k), P1, P1PK, PK
Species Human
Gene Type protein-coding
Description alpha 1,4-galactosyltransferase
Other Description CD77 synthase|GB3 synthase|P blood group (P one antigen)|P(k) antigen synthase|P1/Pk synthase|UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase|alpha-1,4-N-acetylglucosaminyltransferase|alpha4Gal-T1|globotriaosylceramide synthase|lactosylceramide 4-alpha-galactosyltransferase
Swissprots Q9NPC4 B2R7C4 Q9P1X5
Accessions AAO39149 AAO39150 AAO39151 AAO39152 AAP47164 AAP47165 AAP47166 AAP47167 AAP47168 AAP47169 AAP47170 AAQ68076 AAS77212 AAS77213 AAS77214 AAS77215 AAS77216 AAS77217 AAS77218 AAS77219 AAS77220 AAS77221 AAX20109 ABP35532 ABP35533 ABQ10740 ABQ10741 AFM54542 AGF29465 BAA94503 CAC69260 CCB78515 CCH64301 CCH64302 CCH64303 CCH64304 EAW73274 Q9NPC4 AB037883 BAA95915 AJ245581 CAB93532 AK074388 AK130208 AK312927 BAG35771 BC017068 AAH17068 BC055286 AAH55286 CB150578 DQ891619 ABM82545 DQ894811 ABM85737 GU902275 GU902276 GU902277 XM_005261643 XP_005261700 XM_005261644 XP_005261701 XM_005261646 XP_005261703 XM_005261647 XP_005261704 XM_005261648 XP_005261705 XM_006724265 XP_006724328 XM_006724266 XP_006724329 XM_011530233 XP_011528535 XM_011530234 XP_011528536 NM_017436 NP_059132
Function Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins.
Subcellular Location Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Tissue Specificity Ubiquitous. Highly expressed in kidney, heart, spleen, liver, testis and placenta.
Top Pathways Glycosphingolipid biosynthesis - globo series

CD77 synthase CRISPR/Cas9 KO Plasmid (h) - sc-404828 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD77 synthase HDR Plasmid (h) - sc-404828-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD77 synthase Double Nickase Plasmid (h) - sc-404828-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD77 synthase Double Nickase Plasmid (h2) - sc-404828-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD77 synthase CRISPR Activation Plasmid (h) - sc-404828-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD77 synthase CRISPR Activation Plasmid (h2) - sc-404828-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD77 synthase Lentiviral Activation Particles (h) - sc-404828-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD77 synthase Lentiviral Activation Particles (h2) - sc-404828-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD77 synthase siRNA (h) - sc-72831 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CD77 synthase shRNA Plasmid (h) - sc-72831-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CD77 synthase shRNA (h) Lentiviral Particles - sc-72831-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CD77 Synthase RNAi - H00053947-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU014711 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2596 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2596 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

A4GALT siRNA (Human) - CRJ0006 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

A4GALT - MBS8222154 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CD77 synthase CRISPR/Cas9 KO Plasmid (h2) - sc-404828-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD77 synthase HDR Plasmid (h2) - sc-404828-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human A4GALT (NM_017436.4) - SHH228350 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human A4GALT(NM_017436.4) - SHG020791 from Creative biogene

Category siRNA
Species Reactivities Human

A4GALT shRNA Plasmid (Human) - CHJ0006 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

A4GALT miRNA 3'UTR clone - MiUTR1H-00005 from Creative biogene

Species Reactivities Human
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