SERPINB7

Gene Symbol SERPINB7
Entrez Gene 8710
Alt Symbol MEGSIN, PPKN, TP55
Species Human
Gene Type protein-coding
Description serpin peptidase inhibitor, clade B (ovalbumin), member 7
Other Description mesangium predominant gene, megsin|serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 7|serpin B7
Swissprots O75635 F5GZC0 Q3KPG4 B4DUW8 Q1ED45
Accessions EAW63159 O75635 AF027866 AAC64506 AK290673 BAF83362 AK290876 BAF83565 AK300828 BAG62480 BC069417 AAH69417 BC069442 AAH69442 BC069547 AAH69547 BC106743 AAI06744 BC106744 AAI06745 BP332064 BX641156 CAE46069 CD701612 CD702645 D88575 BAA31232 DA577978 XM_006722562 XP_006722625 XM_011526236 XP_011524538 NM_001040147 NP_001035237 NM_001261830 NP_001248759 NM_001261831 NP_001248760 NM_003784 NP_003775
Function Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin.
Subcellular Location Cytoplasm {ECO:0000250}.
Tissue Specificity Predominantly expressed in mesangial cells. Expressed in the epidermis of the whole body. {ECO:0000269|PubMed:24207119}.

megsin (G-16) - sc-79258 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

megsin (I-16) - sc-79259 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

megsin (N-18) - sc-79260 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-SerpinB7 antibody - ab155483 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-SerpinB7 antibody (ab155483) at 1/1000 dilution + NCI-H929 whole cell lysate at 30 µg

Anti-SerpinB7 antibody - ab47740 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab47740 stained HepG2 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab47740, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-SerpinB7 antibody - ab127752 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-SerpinB7 antibody (ab127752) at 1/1000 dilution + NT2D1 whole cell lysate at 30 µg

Anti-SERPINB7 / MEGSIN Antibody - LS-C155689 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: NT2D1 10% SDS PAGE SERPINB7 antibody diluted at 1:1000

Anti-SERPINB7 / MEGSIN Antibody (Internal, AP) - LS-C282625 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SERPINB7 / MEGSIN Antibody (Internal, APC) - LS-C282628 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SERPINB7 / MEGSIN Antibody (aa98-147) - LS-C200657 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from Jurkat cells using SERPINB7 antibody.

Anti-SERPINB7 / MEGSIN Antibody (aa51-100) - LS-C116821 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SERPINB7 antibody LS-C116821 Western blot of PANC1 cell lysate.

Anti-SERPINB7 / MEGSIN Antibody (aa111-160) - LS-C120382 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from Jurkat cells, using SERPINB7 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-SERPINB7 / MEGSIN Antibody (Internal, FITC) - LS-C282629 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SERPINB7 / MEGSIN Antibody (Internal, Biotin) - LS-C282630 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SERPINB7 / MEGSIN Antibody (Internal, Azide-free, HRP) - LS-C282631 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SERPINB7 / MEGSIN Antibody (Internal, PE) - LS-C282632 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SERPINB7 / MEGSIN Antibody (aa157-202) - LS-C313845 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SERPINB7 / MEGSIN Antibody (Internal) - LS-C328631 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SERPINB7 / MEGSIN Antibody (aa108-137) - LS-C168986 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human kidney carcinoma reacted with SERPINB7 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

SerpinB7 Antibody - NBP1-82782 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: SerpinB7 Antibody [NBP1-82782] - Immunohistochemical staining of human skin shows moderate cytoplasmic and nuclear positivity in subsets of keratinocytes.

SerpinB7 Antibody - NBP2-20312 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SerpinB7 Antibody [NBP2-20312] - Sample (30 ug of whole cell lysate) A: NCI-H929 10% SDS PAGE gel, diluted at 1:1000.

SerpinB7 Antibody - NBP2-20313 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SerpinB7 Antibody [NBP2-20313] - Sample (30 ug of whole cell lysate) A: NT2D1 10% SDS PAGE gel, diluted at 1:1000.

SerpinB7 Antibody - H00008710-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: SerpinB7 Antibody [H00008710-D01P] - Analysis of SERPINB7 expression in transfected 293T cell line by SERPINB7 polyclonal antibody.Lane 1: SERPINB7 transfected lysate(42.90 KDa).Lane 2: Non-transfected lysate.

Megsin Polyclonal Antibody - bs-0815R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat kidney tissue with Anti-Megsin Polyclonal Antibody, Unconjugated (bs-0815R) at 1:200, followed by conjugation to the secondary antibody and DAB staining

Megsin Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-0815R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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