Gene Symbol |
SERPINB7
|
Entrez Gene |
8710
|
Alt Symbol |
MEGSIN, PPKN, TP55
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
serpin peptidase inhibitor, clade B (ovalbumin), member 7
|
Other Description |
mesangium predominant gene, megsin|serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 7|serpin B7
|
Swissprots |
O75635 F5GZC0 Q3KPG4 B4DUW8 Q1ED45
|
Accessions |
EAW63159 O75635 AF027866 AAC64506 AK290673 BAF83362 AK290876 BAF83565 AK300828 BAG62480 BC069417 AAH69417 BC069442 AAH69442 BC069547 AAH69547 BC106743 AAI06744 BC106744 AAI06745 BP332064 BX641156 CAE46069 CD701612 CD702645 D88575 BAA31232 DA577978 XM_006722562 XP_006722625 XM_011526236 XP_011524538 NM_001040147 NP_001035237 NM_001261830 NP_001248759 NM_001261831 NP_001248760 NM_003784 NP_003775
|
Function |
Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin.
|
Subcellular Location |
Cytoplasm {ECO:0000250}.
|
Tissue Specificity |
Predominantly expressed in mesangial cells. Expressed in the epidermis of the whole body. {ECO:0000269|PubMed:24207119}.
|