KCNQ3

Gene Symbol KCNQ3
Entrez Gene 3786
Alt Symbol BFNC2, EBN2, KV7.3
Species Human
Gene Type protein-coding
Description potassium channel, voltage gated KQT-like subfamily Q, member 3
Other Description potassium channel subunit alpha KvLQT3|potassium channel, voltage-gated, subfamily Q, member 3|potassium voltage-gated channel subfamily KQT member 3|potassium voltage-gated channel, KQT-like subfamily, member 3|voltage-gated potassium channel subunit Kv7.3
Swissprots E7EQ89 A2VCT8 B4DJY4 O43525
Accessions AAC96101 CAL00146 EAW92141 EAW92142 O43525 AB208890 BAD92127 AF033347 AAB97314 AK094705 AK095711 AK296293 BAG58996 AV728013 BC128576 AAI28577 BC152755 AAI52756 BX538233 XM_005250914 XP_005250971 XM_006716555 XP_006716618 XM_011517026 XP_011515328 NM_001204824 NP_001191753 NM_004519 NP_004510
Function Probably important in the regulation of neuronal excitability. Associates with KCNQ2 or KCNQ5 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Predominantly expressed in brain.

KCNQ3 (C-20)-R - sc-7795-R from Santa Cruz Biotechnology

Prices $61.00
Sizes 100 µg/0.5 ml
Host Rabbit
Clonality Polyclonal

KCNQ3 (H-110) - sc-25702 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

KCNQ3 (N-19) - sc-7794 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
KCNQ3 (N-19): sc-7794. Immunoperoxidase staining of formalin fixed, paraffin-embedded human rectum tissue showing cytoplasmic staining of glandular cells.

Anti-KCNQ3 (phospho T246) antibody - ab62456 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab62456, at 1/50 dilution, staining KCNQ3 in paraffin embedded human brain tissue by Immunohistochemistry in the absence or presence of the immunising peptide.

Anti-KCNQ3 antibody - ab16228 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-KCNQ3 antibody - ab101785 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-KCNQ3 antibody - ab66640 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
IHC image of ab66640 staining in human colon formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab66640, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-KCNQ3 antibody - ab113948 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNQ3 Antibody (N-Terminus) - LS-C144792 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNQ3 Antibody (aa861-872) - LS-C112723 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-KCNQ3 Antibody (aa651-679, AP) - LS-C260964 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNQ3 Antibody (aa651-679, APC) - LS-C260966 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNQ3 Antibody (aa651-679, Biotin) - LS-C260967 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNQ3 Antibody (aa651-679, FITC) - LS-C260968 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNQ3 Antibody (aa651-679, Azide-free, HRP) - LS-C260969 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNQ3 Antibody (aa650-679) - LS-C322405 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNQ3 Antibody (aa651-679, PE) - LS-C260970 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNQ3 Antibody (phospho-Thr246) - LS-C199186 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human brain, using Kv7.3/KCNQ3 (Phospho-Thr246) Antibody. The sample on the right was incubated with synthetic peptide.

Anti-KCNQ3 Antibody (aa191-240) - LS-C199185 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human brain tissue, using Kv7.3/KCNQ3 Antibody. The sample on the right was incubated with synthetic peptide.

Anti-KCNQ3 Antibody (aa580-629) - LS-C135027 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
KCNQ3 antibody LS-C135027 Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.

Anti-KCNQ3 Antibody (aa651-679) - LS-C165446 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
KCNQ3 Antibody western blot of mouse bladder tissue lysates (35 ug/lane). The KCNQ3 antibody detected the KCNQ3 protein (arrow).

Kv7.3 Antibody - NBP1-46666 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Kv7.3 Antibody - NBP1-84023 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: Kv7.3 Antibody [NBP1-84023] - Staining of human rectum shows strong cytoplasmic positivity in glandular cells.

Kv7.3 Antibody - NBP1-36967 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-KCNQ3 antibody produced in rabbit - HPA035212 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-KCNQ3: <B>Cat. No. HPA035212</B>: Immunohistochemical staining of human rectum shows strong cytoplasmic positivity in glandular cells.
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