Gene Symbol | KCNQ3 |
---|---|
Entrez Gene | 3786 |
Alt Symbol | BFNC2, EBN2, KV7.3 |
Species | Human |
Gene Type | protein-coding |
Description | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
Other Description | potassium channel subunit alpha KvLQT3|potassium channel, voltage-gated, subfamily Q, member 3|potassium voltage-gated channel subfamily KQT member 3|potassium voltage-gated channel, KQT-like subfamily, member 3|voltage-gated potassium channel subunit Kv7.3 |
Swissprots | E7EQ89 A2VCT8 B4DJY4 O43525 |
Accessions | AAC96101 CAL00146 EAW92141 EAW92142 O43525 AB208890 BAD92127 AF033347 AAB97314 AK094705 AK095711 AK296293 BAG58996 AV728013 BC128576 AAI28577 BC152755 AAI52756 BX538233 XM_005250914 XP_005250971 XM_006716555 XP_006716618 XM_011517026 XP_011515328 NM_001204824 NP_001191753 NM_004519 NP_004510 |
Function | Probably important in the regulation of neuronal excitability. Associates with KCNQ2 or KCNQ5 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Predominantly expressed in brain. |
KCNQ3 CRISPR/Cas9 KO Plasmid (h) - sc-403544 from Santa Cruz Biotechnology
|
||||||||
KCNQ3 HDR Plasmid (h) - sc-403544-HDR from Santa Cruz Biotechnology
|
||||||||
KCNQ3 Double Nickase Plasmid (h) - sc-403544-NIC from Santa Cruz Biotechnology
|
||||||||
KCNQ3 Double Nickase Plasmid (h2) - sc-403544-NIC-2 from Santa Cruz Biotechnology
|
||||||||
KCNQ3 CRISPR Activation Plasmid (h) - sc-403544-ACT from Santa Cruz Biotechnology
|
||||||||
KCNQ3 CRISPR Activation Plasmid (h2) - sc-403544-ACT-2 from Santa Cruz Biotechnology
|
||||||||
KCNQ3 Lentiviral Activation Particles (h) - sc-403544-LAC from Santa Cruz Biotechnology
|
||||||||
KCNQ3 Lentiviral Activation Particles (h2) - sc-403544-LAC-2 from Santa Cruz Biotechnology
|
||||||||
KCNQ3 siRNA (h) - sc-42501 from Santa Cruz Biotechnology
|
||||||||
KCNQ3 shRNA Plasmid (h) - sc-42501-SH from Santa Cruz Biotechnology
|
||||||||
KCNQ3 shRNA (h) Lentiviral Particles - sc-42501-V from Santa Cruz Biotechnology
|
||||||||
Kv7.3 RNAi - H00003786-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU019611 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN10988 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10988 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR02062 from Sigma-Aldrich
|
||||||||
KCNQ3 siRNA (Human) - CRH2560 from Cohesion Biosciences
|
||||||||
shRNA set against Human KCNQ3 (NM_004519.3) - SHH323667 from Creative biogene
|
||||||||
Human KCNQ3 siRNA - orb263062 from Biorbyt
|
||||||||
KCNQ3 shRNA Plasmid (Human) - CHH2560 from Cohesion Biosciences
|
||||||||
KCNQ3 miRNA 3'UTR clone - MiUTR3H-04798 from Creative biogene
|