Gene Symbol |
KCNQ3
|
Entrez Gene |
3786
|
Alt Symbol |
BFNC2, EBN2, KV7.3
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
potassium channel, voltage gated KQT-like subfamily Q, member 3
|
Other Description |
potassium channel subunit alpha KvLQT3|potassium channel, voltage-gated, subfamily Q, member 3|potassium voltage-gated channel subfamily KQT member 3|potassium voltage-gated channel, KQT-like subfamily, member 3|voltage-gated potassium channel subunit Kv7.3
|
Swissprots |
E7EQ89 A2VCT8 B4DJY4 O43525
|
Accessions |
AAC96101 CAL00146 EAW92141 EAW92142 O43525 AB208890 BAD92127 AF033347 AAB97314 AK094705 AK095711 AK296293 BAG58996 AV728013 BC128576 AAI28577 BC152755 AAI52756 BX538233 XM_005250914 XP_005250971 XM_006716555 XP_006716618 XM_011517026 XP_011515328 NM_001204824 NP_001191753 NM_004519 NP_004510
|
Function |
Probably important in the regulation of neuronal excitability. Associates with KCNQ2 or KCNQ5 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs.
|
Subcellular Location |
Membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Predominantly expressed in brain.
|