TRMT12

Gene Symbol TRMT12
Entrez Gene 55039
Alt Symbol TRM12, TYW2
Species Human
Gene Type protein-coding
Description tRNA methyltransferase 12 homolog (S. cerevisiae)
Other Description alpha-amino-alpha-carboxypropyl transferase TYW2|homolog of yeast tRNA methyltransferase|tRNA methyltranferase 12 homolog|tRNA wybutosine-synthesizing protein 2 homolog|tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase|tRNA-yW synthesizing protein 2|tRNA-yW-synthesizing protein 2
Swissprots Q9NWK6 Q96F21 Q6PKB9 Q53H54
Accessions EAW92062 Q53H54 AA608716 AK000779 BAA91374 AK222727 BAD96447 AK225083 BC003057 AAH03057 BC011713 AAH11713 BP342608 NM_017956 NP_060426
Function S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha- carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86. {ECO:0000269|PubMed:22761755}.

TRM12 (C-13) - sc-87487 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TRM12 (F-16) - sc-87488 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-TRMT12 antibody - ab113103 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TRMT12 antibody (ab113103) at 0.5 µg/mlLane 1 : K562 cell lysateLane 2 : K562 cell lysate with blocking peptideLysates/proteins at 15 µg per lane.

Anti-TRMT12 antibody - ab169687 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-TRMT12 antibody (ab169687) at 1 µg/mlLane 1 : TRMT12 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-TYW2 / TRMT12 Antibody (N-Terminus) - LS-C144381 from LifeSpan Bioscience

Prices $345.00, $1,035.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry of TYW2 in K562 cells with TYW2 antibody at 10 ug/ml.

TRMT12 Antibody - NBP1-83633 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: TRMT12 Antibody [NBP1-83633] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG sp

TRMT12 Antibody - NBP1-76583 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: TRMT12 Antibody [NBP1-76583] - Western blot analysis of TYW2 in K562 cell lysate with TYW2 antibody at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide.

TRMT12 Antibody - H00055039-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: TRMT12 Antibody [H00055039-B01] - analysis of TRMT12 expression in transfected 293T cell line by TRMT12 MaxPab polyclonal antibody. Lane 1: TRMT12 transfected lysate (49.28 KDa). Lane 2: Non-transfected lysate.

TRMT12 Antibody - H00055039-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-TRMT12 antibody produced in rabbit - HPA023939 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TRMT12: <B>Cat. No. HPA023939</B>: Immunohistochemical staining of human colon shows moderate nuclear positivity in glandular cells.

TYW2 antibody - orb75621 from Biorbyt

Prices $723.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of K562 cell lysate at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide using TYW2 antibody

TRMT12 (N-term) antibody - AP26146PU-N from Acris Antibodies

Prices $340.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

TRMT12 antibody - H00055039-B01 from Acris Antibodies

Prices $360.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot analysis of TRMT12 expression in transfected 293T cell line (H00055039-T01) by TRMT12 MaxPab polyclonal antibody.  Lane 1: TRMT12 transfected lysate(49.28 KDa). Lane 2: Non-transfected lysate.

TRMT12 antibody - H00055039-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

TYW2 Antibody - 6375 from ProSci

Prices $79.00, $325.00
Sizes 20 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of TYW2 in K562 cell lysate with TYW2 antibody at 0.5 μg/mL in (A) the absence and (B) the presence of blocking peptide.

TRMT12 antibody - 16201-1-AP from Proteintech Group

Host Rabbit
Clonality Polyclonal

TYW2, Polyclonal Antibody - MBS150690 from MyBioSource

Prices $140.00, $355.00
Sizes 20 µg, 100 µg
Host Rabbit
Clonality Polyclonal

TYW2 Antibody - 254479 from ABBIOTEC

Prices $292.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

TYW2 Antibody - 25315 from Signalway Antibody

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of TYW2 in K562 cell lysate with TYW2 antibody at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide.

Anti-TRMT12 monoclonal antibody - DCABH-13844 from Creative Diagnostics

Host Rabbit
Clonality Monoclonal

Anti-TRMT12 (full length) polyclonal antibody - DPABH-08270 from Creative Diagnostics

Host Mouse
Clonality Polyclonal

Anti-TRMT12 (N-terminal) polyclonal antibody - DPAB-L21367 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

TYW2 Polyclonal Antibody - PA5-21153 from Thermo Fisher Scientific

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of K562 cell lysate using a TYW2 polyclonal antibody (Product # PA5-21153) at 0.5 ug/mL in either (A) the presence and (B) the absence of blocking peptide.

TYW2 Antibody - 600-401-FT3 from Rockland Immunochemicals Inc

Prices $319.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

TYW2 Antibody (OAPB01303) - OAPB01303 from Aviva Systems Biology

Prices $375.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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