Gene Symbol | TRMT12 |
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Entrez Gene | 55039 |
Alt Symbol | TRM12, TYW2 |
Species | Human |
Gene Type | protein-coding |
Description | tRNA methyltransferase 12 homolog (S. cerevisiae) |
Other Description | alpha-amino-alpha-carboxypropyl transferase TYW2|homolog of yeast tRNA methyltransferase|tRNA methyltranferase 12 homolog|tRNA wybutosine-synthesizing protein 2 homolog|tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase|tRNA-yW synthesizing protein 2|tRNA-yW-synthesizing protein 2 |
Swissprots | Q9NWK6 Q96F21 Q6PKB9 Q53H54 |
Accessions | EAW92062 Q53H54 AA608716 AK000779 BAA91374 AK222727 BAD96447 AK225083 BC003057 AAH03057 BC011713 AAH11713 BP342608 NM_017956 NP_060426 |
Function | S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha- carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86. {ECO:0000269|PubMed:22761755}. |
TRM12 (C-13) - sc-87487 from Santa Cruz Biotechnology
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TRM12 (F-16) - sc-87488 from Santa Cruz Biotechnology
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Anti-TRMT12 antibody - ab113103 from Abcam
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Anti-TRMT12 antibody - ab169687 from Abcam
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Anti-TYW2 / TRMT12 Antibody (N-Terminus) - LS-C144381 from LifeSpan Bioscience
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TRMT12 Antibody - NBP1-83633 from Novus Biologicals
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TRMT12 Antibody - NBP1-76583 from Novus Biologicals
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TRMT12 Antibody - H00055039-B01 from Novus Biologicals
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TRMT12 Antibody - H00055039-B01P from Novus Biologicals
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Anti-TRMT12 antibody produced in rabbit - HPA023939 from Sigma-Aldrich
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TYW2 antibody - orb75621 from Biorbyt
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TRMT12 (N-term) antibody - AP26146PU-N from Acris Antibodies
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TRMT12 antibody - H00055039-B01 from Acris Antibodies
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TRMT12 antibody - H00055039-B01P from Acris Antibodies
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TYW2 Antibody - 6375 from ProSci
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TRMT12 antibody - 16201-1-AP from Proteintech Group
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TYW2, Polyclonal Antibody - MBS150690 from MyBioSource
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TYW2 Antibody - 254479 from ABBIOTEC
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TYW2 Antibody - 25315 from Signalway Antibody
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Anti-TRMT12 monoclonal antibody - DCABH-13844 from Creative Diagnostics
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Anti-TRMT12 (full length) polyclonal antibody - DPABH-08270 from Creative Diagnostics
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Anti-TRMT12 (N-terminal) polyclonal antibody - DPAB-L21367 from Creative Diagnostics
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TYW2 Polyclonal Antibody - PA5-21153 from Thermo Fisher Scientific
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TYW2 Antibody - 600-401-FT3 from Rockland Immunochemicals Inc
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TYW2 Antibody (OAPB01303) - OAPB01303 from Aviva Systems Biology
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