TRMT12

Gene Symbol TRMT12
Entrez Gene 55039
Alt Symbol TRM12, TYW2
Species Human
Gene Type protein-coding
Description tRNA methyltransferase 12 homolog (S. cerevisiae)
Other Description alpha-amino-alpha-carboxypropyl transferase TYW2|homolog of yeast tRNA methyltransferase|tRNA methyltranferase 12 homolog|tRNA wybutosine-synthesizing protein 2 homolog|tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase|tRNA-yW synthesizing protein 2|tRNA-yW-synthesizing protein 2
Swissprots Q9NWK6 Q96F21 Q6PKB9 Q53H54
Accessions EAW92062 Q53H54 AA608716 AK000779 BAA91374 AK222727 BAD96447 AK225083 BC003057 AAH03057 BC011713 AAH11713 BP342608 NM_017956 NP_060426
Function S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha- carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86. {ECO:0000269|PubMed:22761755}.

Human TRMT12 full length protein - ab162942 from Abcam

Category Protein
Source Wheat germ
Species Human
ab162942 on a 12.5% SDS-PAGE stained with Coomassie Blue.

TYW2 / TRMT12 Antibody Blocking Peptide - LS-E31127 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

Recombinant Human TRMT12 Protein - H00055039-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

TRMT12 Blocking Peptide - NBP1-76583PEP from Novus Biologicals

Category Peptide
Prices $129.00
Sizes 50 µg
Species Human

TYW2-Antibody-C-term-Blocking-Peptide - BP9305b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

TRMT12 - H00055039-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

TRMT12 - H00055039-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

TRMT12 control peptide - AP26146CP-N from Acris Antibodies

Category Peptide
Prices $135.00
Sizes 50 µg

TYW2 Peptide - 6375P from ProSci

Category Peptide
Species Human
Western blot analysis of TMEM88 in human brain tissue lysate with TMEM88 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

TRMT12 fusion protein - ag9127 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

TRMT12 fusion protein - Ag9258 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Human tRNA wybutosine-synthesizing protein 2 homolog(TRMT12) - CSB-YP687495HU CSB-EP687495HU CSB-BP687495HU CSB-MP687495HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

TRMT12 (full length, N-term HIS tag) - TP760113 from Acris Antibodies

Category Protein
Prices $199.00
Sizes 50 µg
Source E. coli
Species Human
TRMT12

TRMT12 Recombinant Protein Antigen - NBP1-83633PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human
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