Gene Symbol | TRMT12 |
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Entrez Gene | 55039 |
Alt Symbol | TRM12, TYW2 |
Species | Human |
Gene Type | protein-coding |
Description | tRNA methyltransferase 12 homolog (S. cerevisiae) |
Other Description | alpha-amino-alpha-carboxypropyl transferase TYW2|homolog of yeast tRNA methyltransferase|tRNA methyltranferase 12 homolog|tRNA wybutosine-synthesizing protein 2 homolog|tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase|tRNA-yW synthesizing protein 2|tRNA-yW-synthesizing protein 2 |
Swissprots | Q9NWK6 Q96F21 Q6PKB9 Q53H54 |
Accessions | EAW92062 Q53H54 AA608716 AK000779 BAA91374 AK222727 BAD96447 AK225083 BC003057 AAH03057 BC011713 AAH11713 BP342608 NM_017956 NP_060426 |
Function | S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha- carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86. {ECO:0000269|PubMed:22761755}. |
Human TRMT12 full length protein - ab162942 from Abcam
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TYW2 / TRMT12 Antibody Blocking Peptide - LS-E31127 from LifeSpan Bioscience
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Recombinant Human TRMT12 Protein - H00055039-P01 from Novus Biologicals
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TRMT12 Blocking Peptide - NBP1-76583PEP from Novus Biologicals
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TYW2-Antibody-C-term-Blocking-Peptide - BP9305b from Abgent, a WuXi AppTec company
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TRMT12 - H00055039-P01-10 from Acris Antibodies
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TRMT12 - H00055039-P01-25 from Acris Antibodies
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TRMT12 control peptide - AP26146CP-N from Acris Antibodies
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TYW2 Peptide - 6375P from ProSci
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TRMT12 fusion protein - ag9127 from Proteintech Group
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TRMT12 fusion protein - Ag9258 from Proteintech Group
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Recombinant Human tRNA wybutosine-synthesizing protein 2 homolog(TRMT12) - CSB-YP687495HU CSB-EP687495HU CSB-BP687495HU CSB-MP687495HU from Cusabio
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TRMT12 (full length, N-term HIS tag) - TP760113 from Acris Antibodies
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TRMT12 Recombinant Protein Antigen - NBP1-83633PEP from Novus Biologicals
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