| Gene Symbol | TRMT12 |
|---|---|
| Entrez Gene | 55039 |
| Alt Symbol | TRM12, TYW2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| Other Description | alpha-amino-alpha-carboxypropyl transferase TYW2|homolog of yeast tRNA methyltransferase|tRNA methyltranferase 12 homolog|tRNA wybutosine-synthesizing protein 2 homolog|tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase|tRNA-yW synthesizing protein 2|tRNA-yW-synthesizing protein 2 |
| Swissprots | Q9NWK6 Q96F21 Q6PKB9 Q53H54 |
| Accessions | EAW92062 Q53H54 AA608716 AK000779 BAA91374 AK222727 BAD96447 AK225083 BC003057 AAH03057 BC011713 AAH11713 BP342608 NM_017956 NP_060426 |
| Function | S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha- carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86. {ECO:0000269|PubMed:22761755}. |
tRNA methyltransferase 12 homolog (S. cerevisiae) , ELISA Kit - MBS9328823 from MyBioSource
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Human TRMT12 ELISA Kit - E039550 from Biobool
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