Gene Symbol | RAC2 |
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Entrez Gene | 5880 |
Alt Symbol | EN-7, Gx, HSPC022, p21-Rac2 |
Species | Human |
Gene Type | protein-coding |
Description | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
Other Description | Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2)|ras-related C3 botulinum toxin substrate 2|small G protein |
Swissprots | P15153 Q9UDJ4 |
Accessions | AAB22207 EAW60149 EAW60150 EAW60151 EAW60152 EAW60153 P15153 AF077208 AAD27003 AF498965 AAM21112 AK096924 BC001485 AAH01485 BC018735 BC051899 BI908751 BQ934070 BT006919 AAP35565 CR456555 CAG30441 CU013155 CAK54586 CU013443 CAK54885 DQ893288 ABM84214 DQ896620 ABM87619 EU176461 ABW03912 M29871 AAA36538 XM_006724286 XP_006724349 NM_002872 NP_002863 |
Function | Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase. {ECO:0000269|PubMed:1660188}. |
Subcellular Location | Cytoplasm. Note=Membrane-associated when activated. |
Tissue Specificity | Hematopoietic specific. |
Top Pathways | Sphingolipid signaling pathway, Chemokine signaling pathway, cAMP signaling pathway, Choline metabolism in cancer, Rap1 signaling pathway |
Human RAC2 full length protein - ab84655 from Abcam
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Human RAC2 full length protein - ab78684 from Abcam
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Human RAC2 full length protein - ab87665 from Abcam
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Human RAC2 peptide - ab22892 from Abcam
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RAC2 Antibody Blocking Peptide - LS-E25301 from LifeSpan Bioscience
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RAC2 Antibody Blocking Peptide - LS-E21822 from LifeSpan Bioscience
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RAC2 Antibody Blocking Peptide - LS-E9808 from LifeSpan Bioscience
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RAC2 Recombinant Protein - H00005880-P01 from Novus Biologicals
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Recombinant Human RAC2 Protein - NBC1-18403 from Novus Biologicals
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Recombinant Human RAC2 Protein - NBP1-30199 from Novus Biologicals
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RAC2-Antibody-C-term-Blocking-Peptide - BP8839b from Abgent, a WuXi AppTec company
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RAC2 blocking peptide - GTX89951-PEP from GeneTex
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RAC2 Protein (OPPA01760) - OPPA01760 from Aviva Systems Biology
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RAC2 Protein (OPPA02209) - OPPA02209 from Aviva Systems Biology
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Human RAC2, 189a.a protein - orb81301 from Biorbyt
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Human Ras-Related C3 Botulinum Toxin Substrate 2 protein - orb81300 from Biorbyt
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RAC2 peptide - orb218865 from Biorbyt
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RAC2 protein (His tag) - 80R-1182 from Fitzgerald
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RAC2 Blocking Peptide - abx064196 from Abbexa
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RAC2 Peptide - AC21-0129-P from Abcore
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RAC2 (1-189, His-tag) - AR09246PU-L from Acris Antibodies
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RAC2 (1-189, His-tag) - AR09246PU-N from Acris Antibodies
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RAC2 - H00005880-P01-10 from Acris Antibodies
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RAC2 - H00005880-P01-25 from Acris Antibodies
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Ras-Related C3 Botulinum Toxin Substrate 2, Human Recombinant - 228-11351-1 from RayBiotech
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