CCR4

Gene Symbol	CCR4
Entrez Gene	1233
Alt Symbol	CC-CKR-4, CD194, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5
Species	Human
Gene Type	protein-coding
Description	chemokine (C-C motif) receptor 4
Other Description	C-C CKR-4|C-C chemokine receptor type 4|CCR-4|chemokine (C-C) receptor 4
Swissprots	Q9ULY7 Q9ULY6 P51679
Accessions	AAP84352 ABK41942 BAA86965 BAA86966 BAA86967 BAA86968 BAA86969 EAW64440 EAW64441 P51679 AK292674 BAF85363 BC069139 AAH69139 BC071751 AAH71751 BC074935 AAH74935 CD639869 CD640816 NM_005508 NP_005499
Function	High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. {ECO:0000269|PubMed:10466728, ECO:0000269|PubMed:10754297, ECO:0000269|PubMed:16137713, ECO:0000269|PubMed:9169480, ECO:0000269|PubMed:9430724}.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Predominantly expressed in the thymus, in peripheral blood leukocytes, including T-cells, mostly CD4+ cells, and basophils, and in platelets; at lower levels, in the spleen and in monocytes. Detected also in macrophages, IL-2-activated natural killer cells and skin-homing memory T-cells, mostly the ones expressing the cutaneous lymphocyte antigen (CLA). Expressed in brain microvascular and coronary artery endothelial cells. {ECO:0000269|PubMed:10754297}.
Top Pathways	Cytokine-cytokine receptor interaction, Chemokine signaling pathway, Viral carcinogenesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CCR4 ELISA Kit (Sandwich ELISA) - LS-F9689 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 0.058 ng/ml Range 0.156-10 ng/ml

Human CCR4 ELISA Kit (Sandwich ELISA) - LS-F11069 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

Human CCR4 ELISA Kit - abx150983 from Abbexa Category ELISA Kit Sensitivity 0.063 ng/ml Range 0.156 ng/ml - 10 ng/ml

C-C chemokine receptor type 4, CCR4, Human, ELISA Kit - E1920h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

Chemokine C-C-Motif Receptor 4 (CCR4), Human, ELISA Kit - SEB920Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 0.063ng/mL Range 0.156-10ng/mL

Human CCR4(Chemokine C-C-Motif Receptor 4) ELISA Kit - E-EL-H5489 from Elabscience Category ELISA Kit Sensitivity 46.88 pg/mL Range 78.13—5000 pg/mL

CC Chemokine receptor 4 (CCR-4), ELISA Kit - MBS9311046 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CC Chemokine receptor 4, CCR-4, ELISA Kit - MBS9302106 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CC Chemokine receptor 4, CCR-4, ELISA Kit - MBS9301171 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4, ELISA Kit - MBS2516056 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 46.875pg/ mL Range 78.125-5000pg/ mL

CCR4, ELISA Kit - MBS2516141 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 46.875pg/ mL Range 78.125-5000pg/ mL

ELISA Kit for Chemokine C-C-Motif Receptor 4 (CCR4) - SEB920Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.056ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

CCR-4, Human - DP-10037-X from Nordic BioSite

CCR-4, Mouse - DP-10046-X from Nordic BioSite

ELISA Kit for Chemokine C-C-Motif Receptor 4 (CCR4) - SEB920Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.056ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Dog CCR4 ELISA Kit (Custom ELISA) - LS-F18819 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Mouse CCR4 ELISA Kit (Sandwich ELISA) - LS-F18820 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 Range 0.156-10 ng/ml

HumanCCR4(Chemokine C-C-Motif Receptor 4) ELISA Kit - E-EL-H5489 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 46.88 pg/mL Range 78.13~5000 pg/mL

HumanCXCR4(Chemokine C-X-C-Motif Receptor) ELISA Kit - E-EL-H5490 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 46.88 pg/mL Range 78.13~5000 pg/mL

Human C-C chemokine receptor type 4 ELISA Kit - abx251325 from Abbexa Category ELISA Kit Sensitivity 46.875 pg/ml Range 78.125 pg/ml - 5000 pg/ml

Carbon Catabolite Repression 4 Like Protein (CCRN4L), Human, ELISA Kit - DL-CCRN4L-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

Human CCR4 ELISA Kit - abx571916 from Abbexa Category ELISA Kit Sensitivity 0.063 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human C-C chemokine receptor type 4 ELISA Kit - EKE54055 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.078 ng/mL Range 0.156-10 ng/mL

CCR4 - EKH4002 from Nordic BioSite Sensitivity 46.875pg/ ml Range 78.125--5000pg/ ml

CCR4 ELISA Kit (Human) : 96 Wells (OKEH01368) - OKEH01368 from Aviva Systems Biology Category ELISA Kit Prices $420.00 Sizes 96 wells Sensitivity < 0.078 ng/mL Range 0.156 - 10 ng/mL

Search more