Gene Symbol | ADSSL1 |
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Entrez Gene | 122622 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | adenylosuccinate synthase like 1 |
Other Description | AMPSase 1|IMP--aspartate ligase 1|M-type adenylosuccinate synthetase|adSS 1|adenylosuccinate synthetase isozyme 1|adenylosuccinate synthetase, basic isozyme|adenylosuccinate synthetase, muscle isozyme |
Swissprots | Q86TT6 Q8N142 Q8N714 |
Accessions | EAW81876 Q8N142 AK054648 AK095921 BAC04649 AK096124 BAG53216 AK096720 BAG53356 AY037159 AAK67646 BC032039 AAH32039 BC047904 AAH47904 BX248286 CAD62614 XM_006720026 XP_006720089 XM_011536412 XP_011534714 XM_011536413 XP_011534715 XM_011536414 XP_011534716 XM_011536415 XP_011534717 NM_152328 NP_689541 NM_199165 NP_954634 |
Function | Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03126, ECO:0000269|PubMed:15786719}. |
Tissue Specificity | Predominantly expressed in skeletal muscle and heart, as well as in several hematopoietic cell lines and solid tumors. {ECO:0000269|PubMed:15786719}. |
Top Pathways | Purine metabolism, Alanine, aspartate and glutamate metabolism |
AdSS1 (G-9) - sc-166401 from Santa Cruz Biotechnology
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AdSS1 (H-2) - sc-166470 from Santa Cruz Biotechnology
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AdSS1 (K-12) - sc-30468 from Santa Cruz Biotechnology
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AdSS1 (N-16) - sc-30467 from Santa Cruz Biotechnology
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Anti-ADSSL1 antibody - ab85586 from Abcam
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Anti-ADSSL1 antibody - N-terminal - ab107026 from Abcam
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Anti-ADSSL1 Antibody (aa96-123, AP) - LS-C232451 from LifeSpan Bioscience
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Anti-ADSSL1 Antibody (aa96-123, APC) - LS-C232452 from LifeSpan Bioscience
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Anti-ADSSL1 Antibody (aa96-123, FITC) - LS-C232454 from LifeSpan Bioscience
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Anti-ADSSL1 Antibody (aa96-123, Biotin) - LS-C232453 from LifeSpan Bioscience
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Anti-ADSSL1 Antibody (aa96-123, Azide-free, HRP) - LS-C249381 from LifeSpan Bioscience
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Anti-ADSSL1 Antibody (aa96-123, PE) - LS-C232455 from LifeSpan Bioscience
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Anti-ADSSL1 Antibody (aa369-437) - LS-C306121 from LifeSpan Bioscience
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Anti-ADSSL1 Antibody (aa103-131) - LS-C319356 from LifeSpan Bioscience
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Anti-ADSSL1 Antibody (aa144-193) - LS-C102304 from LifeSpan Bioscience
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Anti-ADSSL1 Antibody (aa96-123) - LS-C156121 from LifeSpan Bioscience
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ADSSL1 Antibody - NBP1-55524 from Novus Biologicals
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ADSSL1 Antibody (2D12) - H00122622-M01 from Novus Biologicals
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Anti-ADSSL1 antibody produced in rabbit - SAB2100066 from Sigma-Aldrich
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Anti-ADSSL1 (191-205) antibody produced in rabbit - SAB1102897 from Sigma-Aldrich
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Monoclonal Anti-ADSSL1 antibody produced in mouse - SAB1401979 from Sigma-Aldrich
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Anti-ADSSL1 (411-425) antibody produced in rabbit - SAB1102898 from Sigma-Aldrich
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ADSSL1 antibody - middle region (ARP48442_P050) - ARP48442_P050 from Aviva Systems Biology
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ADSSL1 Antibody - N-terminal region (OAAB03274) - OAAB03274 from Aviva Systems Biology
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ADSSL1-Antibody-N-term - AP5873a from Abgent, a WuXi AppTec company
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