Gene Symbol | ADSSL1 |
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Entrez Gene | 122622 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | adenylosuccinate synthase like 1 |
Other Description | AMPSase 1|IMP--aspartate ligase 1|M-type adenylosuccinate synthetase|adSS 1|adenylosuccinate synthetase isozyme 1|adenylosuccinate synthetase, basic isozyme|adenylosuccinate synthetase, muscle isozyme |
Swissprots | Q86TT6 Q8N142 Q8N714 |
Accessions | EAW81876 Q8N142 AK054648 AK095921 BAC04649 AK096124 BAG53216 AK096720 BAG53356 AY037159 AAK67646 BC032039 AAH32039 BC047904 AAH47904 BX248286 CAD62614 XM_006720026 XP_006720089 XM_011536412 XP_011534714 XM_011536413 XP_011534715 XM_011536414 XP_011534716 XM_011536415 XP_011534717 NM_152328 NP_689541 NM_199165 NP_954634 |
Function | Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03126, ECO:0000269|PubMed:15786719}. |
Tissue Specificity | Predominantly expressed in skeletal muscle and heart, as well as in several hematopoietic cell lines and solid tumors. {ECO:0000269|PubMed:15786719}. |
Top Pathways | Purine metabolism, Alanine, aspartate and glutamate metabolism |
Human ADSSL1 full length protein - ab165184 from Abcam
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Human ADSSL1 protein fragment - ab165185 from Abcam
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ADSSL1 Antibody Blocking Peptide - LS-E8020 from LifeSpan Bioscience
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ADSSL1 Antibody Blocking Peptide - LS-E17524 from LifeSpan Bioscience
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Recombinant Human ADSSL1 Protein - H00122622-P01 from Novus Biologicals
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Recombinant Human ADSSL1 Protein - H00122622-Q01 from Novus Biologicals
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ADSSL1-Antibody-N-term-Blocking-peptide - BP5873a from Abgent, a WuXi AppTec company
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ADSSL1 Blocking Peptide - 33R-9461 from Fitzgerald
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ADSSL1 - H00122622-P01-10 from Acris Antibodies
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ADSSL1 - H00122622-P01-25 from Acris Antibodies
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ADSSL1 - H00122622-Q01-10 from Acris Antibodies
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ADSSL1 - H00122622-Q01-25 from Acris Antibodies
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ADSSL1 fusion protein - ag11756 from Proteintech Group
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ADSSL1 fusion protein - ag11632 from Proteintech Group
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Recombinant Human Adenylosuccinate synthetase isozyme 1(ADSSL1) - CSB-YP836641HU CSB-EP836641HU CSB-BP836641HU CSB-MP836641HU from Cusabio
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Adenylosuccinate synthetase isozyme 1(ADSSL1) - MBS1471384 from MyBioSource
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ADSSL1 (transcript variant 2) - TP308536 from Acris Antibodies
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ADSSL1 Peptide, Human - M34GP00341H from Creative Peptides
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