IL1B

Gene Symbol	IL1B
Entrez Gene	3553
Alt Symbol	IL-1, IL1-BETA, IL1F2
Species	Human
Gene Type	protein-coding
Description	interleukin 1, beta
Other Description	IL-1 beta|catabolin|interleukin-1 beta|preinterleukin 1 beta|pro-interleukin-1-beta
Swissprots	Q53X59 P01584 Q9UCT6 Q7RU01 Q7M4S7 Q96HE5 Q53XX2
Accessions	AAA74137 AAM88883 AAX88888 CAA28185 CAD29872 CCA63968 EAW73605 EAW73606 EAW73607 P01584 AB451494 BAG70308 AF043335 AAC03536 AK313983 BC008678 AAH08678 BT007213 AAP35877 CR407679 CAG28607 DQ890673 ABM81599 DQ893854 ABM84780 K02770 AAA36106 M15330 AAA59135 M54933 AAA59136 X02532 CAA26372 X56087 CAA39567 XM_006712496 XP_006712559 NM_000576 NP_000567
Function	Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. {ECO:0000269|PubMed:3920526}.
Subcellular Location	Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
Top Pathways	Herpes simplex infection, Tuberculosis, Legionellosis, TNF signaling pathway, Salmonella infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IL-1 beta (Interleukin-1 beta) Human ELISA Kit - ab100562 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 0.3 pg/ml Range 0.48 pg/ml - 100 pg/ml

IL-1 beta (Interleukin-1 beta) Human ELISA Kit - ab46052 from Abcam Category ELISA Kit Prices $489.00, $734.00 Sizes 1 x 96 tests, 2 x 96 tests Sensitivity 6.5 pg/ml Range 15.6 pg/ml - 500 pg/ml

IL-1 beta (Interleukin-1 beta) Human SimpleStep ELISA™ Kit - ab184861 from Abcam Category ELISA Kit Prices $484.00 Sizes 1 x 96 tests Sensitivity 5.9 pg/ml Range 5 pg/ml - 5000 pg/ml

IL-1 beta (Interleukin-1 beta) Human ELISA Kit - ab108865 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity > 3.9 pg/ml Range 3.91 pg/ml - 250 pg/ml

IL1 beta Human ELISA Set (without plates) - ab47351 from Abcam Prices $557.00, $636.00, $765.00 Sizes 5 x 96 tests, 10 x 96 tests, 15 x 96 tests Sensitivity < 5 pg/ml Range 15.6 pg/ml - 500 pg/ml

IL1 beta Human Elispot Kit - ab46608 from Abcam Category ELISA Kit Prices $937.00, $1,563.00 Sizes 5 x 96 tests, 10 x 96 tests

IL1 Beta Human Elispot Kit - ab62924 from Abcam Category ELISA Kit Prices $339.00, $937.00 Sizes 1 x 96 tests, 5 x 96 tests

IL1 beta Human Elispot Kit (Reagents for 10 x 96 tests, without plates) - ab46631 from Abcam Category ELISA Kit Prices $1,021.00 Sizes 10 x 96 tests

IL1 beta Human Elispot Kit (without plates) - ab46578 from Abcam Category ELISA Kit Prices $729.00, $1,021.00, $1,359.00, $1,614.00 Sizes 5 x 96 tests, 10 x 96 tests, 15 x 96 tests, 20 x 96 tests

Human IL-1B / IL-1 Beta ELISA Kit (Sandwich ELISA) - LS-F2461 from LifeSpan Bioscience Category ELISA Kit Prices $410.00 Sizes 1 plate Sensitivity 0.15 pg/ml Range 7.81-500 pg/ml

Rat IL-1B / IL-1 Beta ELISA Kit (Sandwich ELISA) - LS-F2462 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Sensitivity 1 pg/ml Range 7.81-500 pg/ml

Mouse IL-1B / IL-1 Beta ELISA Kit (Sandwich ELISA) - LS-F2463 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 1 pg/ml Range 7.81-500 pg/ml

Human IL-1B / IL-1 Beta ELISA Kit (Sandwich ELISA) - LS-F5625 from LifeSpan Bioscience Category ELISA Kit Prices $460.00 Sizes 1 plate Sensitivity 5.8 pg/ml Range 7.81-500 pg/ml

Mouse IL-1B / IL-1 Beta ELISA Kit (Sandwich ELISA) - LS-F5626 from LifeSpan Bioscience Category ELISA Kit Prices $520.00 Sizes 1 plate Sensitivity 15.6 pg/ml Range 7.81-500 pg/ml

Rat IL-1B / IL-1 Beta ELISA Kit (Sandwich ELISA) - LS-F5627 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Sensitivity 6.25 pg/ml Range 7.81-500 pg/ml

Dog IL-1B / IL-1 Beta ELISA Kit (Sandwich ELISA) - LS-F5889 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 7.81 pg/ml Range 7.81-500 pg/ml

Chicken IL-1B / IL-1 Beta ELISA Kit (Sandwich ELISA) - LS-F4677 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 7.81 pg/ml Range 7.81-500 pg/ml

Rabbit IL-1B / IL-1 Beta ELISA Kit (Sandwich ELISA) - LS-F5368 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Sensitivity 3.12 pg/ml Range 7.81-500 pg/ml

Pig IL-1B / IL-1 Beta ELISA Kit (Sandwich ELISA) - LS-F5326 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 5.7 pg/ml Range 7.81-500 pg/ml

Guinea pig IL-1B / IL-1 Beta ELISA Kit (Sandwich ELISA) - LS-F5694 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 2.8 pg/ml Range 7.81-500 pg/ml

Horse IL-1B / IL-1 Beta ELISA Kit (Sandwich ELISA) - LS-F7102 from LifeSpan Bioscience Category ELISA Kit Prices $790.00 Sizes 1 plate Sensitivity 15.63 pg/ml Range 7.81-500 pg/ml

Rat IL-1B / IL-1 Beta ELISA Kit (Sandwich ELISA) - LS-F981 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 7.81-500 pg/ml

Human IL-1B / IL-1 Beta ELISA Kit (Sandwich ELISA) - LS-F990 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 7.81-500 pg/ml

Mouse IL-1B / IL-1 Beta ELISA Kit (Sandwich ELISA) - LS-F971 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 7.81-500 pg/ml

Bovine IL-1B / IL-1 Beta ELISA Kit (Sandwich ELISA) - LS-F7588 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 15.63 pg/ml Range 7.81-500 pg/ml

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