IL1B

Gene Symbol IL1B
Entrez Gene 3553
Alt Symbol IL-1, IL1-BETA, IL1F2
Species Human
Gene Type protein-coding
Description interleukin 1, beta
Other Description IL-1 beta|catabolin|interleukin-1 beta|preinterleukin 1 beta|pro-interleukin-1-beta
Swissprots Q53X59 P01584 Q9UCT6 Q7RU01 Q7M4S7 Q96HE5 Q53XX2
Accessions AAA74137 AAM88883 AAX88888 CAA28185 CAD29872 CCA63968 EAW73605 EAW73606 EAW73607 P01584 AB451494 BAG70308 AF043335 AAC03536 AK313983 BC008678 AAH08678 BT007213 AAP35877 CR407679 CAG28607 DQ890673 ABM81599 DQ893854 ABM84780 K02770 AAA36106 M15330 AAA59135 M54933 AAA59136 X02532 CAA26372 X56087 CAA39567 XM_006712496 XP_006712559 NM_000576 NP_000567
Function Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. {ECO:0000269|PubMed:3920526}.
Subcellular Location Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
Top Pathways Herpes simplex infection, Tuberculosis, Legionellosis, TNF signaling pathway, Salmonella infection

IL-1β siRNA (h) - sc-39615 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-1β shRNA Plasmid (h) - sc-39615-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-1β shRNA (h) Lentiviral Particles - sc-39615-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU023751 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1098 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1098 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04573 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04573

IL1B siRNA (Human) - CRH2372 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IL-1 beta/IL-1F2 RNAi - H00003553-R01 from Novus Biologicals

Category siRNA
Prices $339.00, $399.00
Sizes 10 nmol, 20 nmol
Species Reactivities Human

IL1B - MBS8233035 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human IL1B (NM_000576.2) - SHH318489 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human IL1B(NM_000576.2) - SHL171910 from Creative biogene

Category siRNA
Species Reactivities Human

Human IL1B siRNA - orb262874 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IL1B shRNA Plasmid (Human) - CHH2372 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

IL1B miRNA 3'UTR clone - MiUTR1H-04888 from Creative biogene

Species Reactivities Human
Search more