TTBK1

Gene Symbol TTBK1
Entrez Gene 84630
Alt Symbol BDTK
Species Human
Gene Type protein-coding
Description tau tubulin kinase 1
Other Description brain-derived tau kinase|tau-tubulin kinase 1
Swissprots Q6ZNH0 Q2L6C6 A2A2U5 Q96JH2 Q5TCY1 Q8N444
Accessions CCQ43769 EAX04167 EAX04168 EAX04169 Q5TCY1 AB058758 BAB47484 AB218664 BAE78660 AK055425 AK131217 BAD18405 AL833256 BC036764 AAH36764 BC156452 AAI56453 BC172528 AAI72528 XM_011514945 XP_011513247 XM_011514946 XP_011513248 XM_011514947 XP_011513249 XM_011514948 XP_011513250 NM_032538 NP_115927
Function Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU. {ECO:0000269|PubMed:16923168}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:16923168}.
Tissue Specificity Expressed in the brain, particularly in cortical and hippocampal neurons. Weakly expressed in spinal cord and testis. No expression in adipose tissue, bladder, cervix, colon, esophagus, heart, kidney, liver, lung, ovary, placenta, prostate, skeletal muscle, small intestine, spleen, testis, thymus, thyroid or trachea. {ECO:0000269|PubMed:16923168}.

TTBK1 (B-6) - sc-374600 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TTBK1 (B-6): sc-374600. Western blot analysis of TTBK1 expression in Jurkat whole cell lysate.

TTBK1 (E-14) - sc-133330 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
TTBK1 (E-14): sc-133330. Immunofluorescence staining of methanol-fixed NIH/3T3 cells showing cytoskeletal localization.

TTBK1 (P-12) - sc-133331 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
TTBK1 (P-12): sc-133331. Immunofluorescence staining of methanol-fixed NIH/3T3 cells showing cytoskeletal localization.

Anti-TTBK1 antibody - ab103944 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ab103944 stained SKNSH cells. The cells were 4% formalehyde fixed for 10 minutes at room temperature and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1hour at room temperature to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab103944 at 5µg/ml) overnight at +4°C. The secondary antibody (pseudo-colored green) was Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) preadsorbed (ab150081) used at a 1/1000 dilution for 1hour at room temperature. Alexa Fluor® 594 WGA was used to label plasma membranes (pseudo-colored red) at a 1/200 dilution for 1hour at room temperature. DAPI was used to stain the cell nuclei (pseudo-colored blue) at a concentration of 1.43µM for 1hour at room temperature.

Anti-TTBK1 antibody - ab106521 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-TTBK1 antibody (ab106521) at 1 µg/ml + Jurkat cell lysate at 15 µg

Anti-TTBK1 antibody - ab113747 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TTBK1 antibody (ab113747) at 1 µg/ml + Jurkat lysate

Anti-TTBK1 antibody - ab156252 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-TTBK1 antibody (ab156252) at 1/100 dilution + HepG2 cell line lysate at 35 µg

Anti-TTBK1 Antibody (aa667-695, AP) - LS-C224499 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TTBK1 Antibody (aa667-695, Biotin) - LS-C224500 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TTBK1 Antibody (aa667-695, APC) - LS-C224501 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TTBK1 Antibody (aa667-695, FITC) - LS-C224502 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TTBK1 Antibody (aa667-695, Azide-free, HRP) - LS-C224503 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TTBK1 Antibody (aa667-695, PE) - LS-C224504 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TTBK1 Antibody (aa230-258, APC) - LS-C224506 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TTBK1 Antibody (aa230-258, AP) - LS-C224505 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TTBK1 Antibody (aa230-258, FITC) - LS-C224508 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TTBK1 Antibody (aa230-258, Biotin) - LS-C224507 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TTBK1 Antibody (aa230-258, PE) - LS-C224510 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TTBK1 Antibody (aa230-258, Azide-free, HRP) - LS-C224509 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TTBK1 Antibody (aa667-695) - LS-C157002 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
TTBK1 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The TTBK1 antibody detected the TTBK1 protein (arrow).

Anti-TTBK1 Antibody (aa667-695) - LS-C326068 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TTBK1 Antibody (aa240-270) - LS-C326070 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TTBK1 Antibody (aa230-258) - LS-C157003 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
TTBK1 Antibody IHC of formalin-fixed and paraffin-embedded brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-TTBK1 Antibody (C-Terminus) IHC-plus™ - LS-B4990 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TTBK1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4990 concentration 5 ug/ml.

TTBK1 Antibody - NBP1-82888 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: TTBK1 Antibody [NBP1-82888] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).
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