TTBK1
| Gene Symbol | TTBK1 |
|---|---|
| Entrez Gene | 84630 |
| Alt Symbol | BDTK |
| Species | Human |
| Gene Type | protein-coding |
| Description | tau tubulin kinase 1 |
| Other Description | brain-derived tau kinase|tau-tubulin kinase 1 |
| Swissprots | Q6ZNH0 Q2L6C6 A2A2U5 Q96JH2 Q5TCY1 Q8N444 |
| Accessions | CCQ43769 EAX04167 EAX04168 EAX04169 Q5TCY1 AB058758 BAB47484 AB218664 BAE78660 AK055425 AK131217 BAD18405 AL833256 BC036764 AAH36764 BC156452 AAI56453 BC172528 AAI72528 XM_011514945 XP_011513247 XM_011514946 XP_011513248 XM_011514947 XP_011513249 XM_011514948 XP_011513250 NM_032538 NP_115927 |
| Function | Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU. {ECO:0000269|PubMed:16923168}. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16923168}. |
| Tissue Specificity | Expressed in the brain, particularly in cortical and hippocampal neurons. Weakly expressed in spinal cord and testis. No expression in adipose tissue, bladder, cervix, colon, esophagus, heart, kidney, liver, lung, ovary, placenta, prostate, skeletal muscle, small intestine, spleen, testis, thymus, thyroid or trachea. {ECO:0000269|PubMed:16923168}. |
TTBK1 overexpression lysate - LY410065 from Acris Antibodies
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TTBK1 Overexpression Lysate (Native) - NBP2-06008 from Novus Biologicals
![Western Blot: TTBK1 Overexpression Lysate (Adult Normal) [NBP2-06008] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TTBK1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1953_TTBK1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06008-img0001.jpg)
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TTBK1 (h): 293T Lysate - sc-372337 from Santa Cruz Biotechnology
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Panoply™ Human TTBK1 Knockdown Stable Cell Line - CSC-DC016775 from Creative biogene
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