Gene Symbol | TTBK1 |
---|---|
Entrez Gene | 84630 |
Alt Symbol | BDTK |
Species | Human |
Gene Type | protein-coding |
Description | tau tubulin kinase 1 |
Other Description | brain-derived tau kinase|tau-tubulin kinase 1 |
Swissprots | Q6ZNH0 Q2L6C6 A2A2U5 Q96JH2 Q5TCY1 Q8N444 |
Accessions | CCQ43769 EAX04167 EAX04168 EAX04169 Q5TCY1 AB058758 BAB47484 AB218664 BAE78660 AK055425 AK131217 BAD18405 AL833256 BC036764 AAH36764 BC156452 AAI56453 BC172528 AAI72528 XM_011514945 XP_011513247 XM_011514946 XP_011513248 XM_011514947 XP_011513249 XM_011514948 XP_011513250 NM_032538 NP_115927 |
Function | Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU. {ECO:0000269|PubMed:16923168}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16923168}. |
Tissue Specificity | Expressed in the brain, particularly in cortical and hippocampal neurons. Weakly expressed in spinal cord and testis. No expression in adipose tissue, bladder, cervix, colon, esophagus, heart, kidney, liver, lung, ovary, placenta, prostate, skeletal muscle, small intestine, spleen, testis, thymus, thyroid or trachea. {ECO:0000269|PubMed:16923168}. |
TTBK1 CRISPR/Cas9 KO Plasmid (h) - sc-403998 from Santa Cruz Biotechnology
|
||||||||
TTBK1 HDR Plasmid (h) - sc-403998-HDR from Santa Cruz Biotechnology
|
||||||||
TTBK1 Double Nickase Plasmid (h) - sc-403998-NIC from Santa Cruz Biotechnology
|
||||||||
TTBK1 Double Nickase Plasmid (h2) - sc-403998-NIC-2 from Santa Cruz Biotechnology
|
||||||||
TTBK1 CRISPR Activation Plasmid (h) - sc-403998-ACT from Santa Cruz Biotechnology
|
||||||||
TTBK1 CRISPR Activation Plasmid (h2) - sc-403998-ACT-2 from Santa Cruz Biotechnology
|
||||||||
TTBK1 Lentiviral Activation Particles (h) - sc-403998-LAC from Santa Cruz Biotechnology
|
||||||||
TTBK1 Lentiviral Activation Particles (h2) - sc-403998-LAC-2 from Santa Cruz Biotechnology
|
||||||||
TTBK1 siRNA (h) - sc-95141 from Santa Cruz Biotechnology
|
||||||||
TTBK1 shRNA Plasmid (h) - sc-95141-SH from Santa Cruz Biotechnology
|
||||||||
TTBK1 shRNA (h) Lentiviral Particles - sc-95141-V from Santa Cruz Biotechnology
|
||||||||
MISSION® siRNA - SIHK2372 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK2373 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK2374 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN22147 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22147 from Sigma-Aldrich
|
||||||||
TTBK1 siRNA (Human) - CRJ3544 from Cohesion Biosciences
|
||||||||
TTBK1 RNAi - H00084630-R02 from Novus Biologicals
|
||||||||
TTBK1 - MBS8227098 from MyBioSource
|
||||||||
shRNA set against Human Ttbk1 (NM_032538.1) - SHH436728 from Creative biogene
|
||||||||
Human TTBK1 siRNA - orb274045 from Biorbyt
|
||||||||
TTBK1 shRNA Plasmid (Human) - CHJ3544 from Cohesion Biosciences
|
||||||||
TTBK1 miRNA 3'UTR clone - MiUTR1H-10838 from Creative biogene
|