Gene Symbol |
ALDH8A1
|
Entrez Gene |
64577
|
Alt Symbol |
ALDH12, DJ352A20.2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
aldehyde dehydrogenase 8 family, member A1
|
Other Description |
aldehyde dehydrogenase 12|aldehyde dehydrogenase family 8 member A1|aldehyde dehydrogenase family protein
|
Swissprots |
Q53GT3 O60793 Q9H2A2 Q5TI80 Q24JS9 B7Z521
|
Accessions |
EAW47985 EAW47986 Q9H2A2 AF303134 AAG42417 AK074266 AK222848 BAD96568 AK290784 BAF83473 AK298325 BAH12757 BC020849 BC113862 AAI13863 BC114473 AAI14474 BF590409 BX647324 DA635162 XM_006715551 XP_006715614 NM_001193480 NP_001180409 NM_022568 NP_072090 NM_170771 NP_739577
|
Function |
Converts 9-cis-retinal to 9-cis-retinoic acid. Has lower activity towards 13-cis-retinal. Has much lower activity towards all-trans-retinal. Has highest activity with benzaldehyde and decanal (in vitro). Has a preference for NAD, but shows considerable activity with NADP (in vitro). {ECO:0000269|PubMed:11007799}.
|
Subcellular Location |
Cytoplasm {ECO:0000250}.
|
Tissue Specificity |
Highly expressed in adult kidney and liver. Detected at lower levels in fetal liver and kidney. {ECO:0000269|PubMed:11007799}.
|