Gene Symbol | ALDH8A1 |
---|---|
Entrez Gene | 64577 |
Alt Symbol | ALDH12, DJ352A20.2 |
Species | Human |
Gene Type | protein-coding |
Description | aldehyde dehydrogenase 8 family, member A1 |
Other Description | aldehyde dehydrogenase 12|aldehyde dehydrogenase family 8 member A1|aldehyde dehydrogenase family protein |
Swissprots | Q53GT3 O60793 Q9H2A2 Q5TI80 Q24JS9 B7Z521 |
Accessions | EAW47985 EAW47986 Q9H2A2 AF303134 AAG42417 AK074266 AK222848 BAD96568 AK290784 BAF83473 AK298325 BAH12757 BC020849 BC113862 AAI13863 BC114473 AAI14474 BF590409 BX647324 DA635162 XM_006715551 XP_006715614 NM_001193480 NP_001180409 NM_022568 NP_072090 NM_170771 NP_739577 |
Function | Converts 9-cis-retinal to 9-cis-retinoic acid. Has lower activity towards 13-cis-retinal. Has much lower activity towards all-trans-retinal. Has highest activity with benzaldehyde and decanal (in vitro). Has a preference for NAD, but shows considerable activity with NADP (in vitro). {ECO:0000269|PubMed:11007799}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Highly expressed in adult kidney and liver. Detected at lower levels in fetal liver and kidney. {ECO:0000269|PubMed:11007799}. |