Gene Symbol | PSKH1 |
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Entrez Gene | 5681 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | protein serine kinase H1 |
Other Description | PSK-H1|serine/threonine-protein kinase H1 |
Swissprots | P11801 Q9NY19 |
Accessions | EAW83185 P11801 AJ272212 CAB91984 AK309272 BC021584 BC037560 BC062616 AAH62616 DA429976 M14504 AAA36519 NM_006742 NP_006733 |
Function | May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role in intranuclear SR protein (non-snRNP splicing factors containing a serine/arginine-rich domain) trafficking and pre-mRNA processing. {ECO:0000269|PubMed:12466556}. |
Subcellular Location | Golgi apparatus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus speckle. Endoplasmic reticulum membrane; Lipid-anchor. Cell membrane; Lipid-anchor. Cytoplasm. Note=Localized in the brefeldin A- sensitive Golgi compartment, at centrosomes, in the nucleus with a somewhat speckle-like presence, membrane-associated to the endoplasmic reticulum (ER) and the plasma membrane (PM), and more diffusely in the cytoplasm. Found to concentrate in splicing factor compartments (SFCs) within the nucleus of interphase cells. The acylation-negative form may be only cytoplasmic and nuclear. Acylation seems to allow the sequestering to the intracellular membranes. Myristoylation may mediate targeting to the intracellular non-Golgi membranes and palmitoylation may mediate the targeting to the Golgi membranes. Dual acylation is required to stabilize the interaction with Golgi membranes. |
Tissue Specificity | Expressed in all tissues and cell lines tested with the highest level of abundance in testis. {ECO:0000269|PubMed:11087665}. |
Human PSKH1 full length protein - ab131708 from Abcam
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Human PSKH1 protein fragment - ab159257 from Abcam
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PSKH1 Antibody Blocking Peptide - LS-E20636 from LifeSpan Bioscience
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PSKH1 Antibody Blocking Peptide - LS-E8742 from LifeSpan Bioscience
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Recombinant Human PSKH1 Protein - H00005681-Q01 from Novus Biologicals
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PSKH1-Antibody-N-term-H70-Blocking-Peptide - BP7179c from Abgent, a WuXi AppTec company
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PSKH1 - H00005681-Q01-10 from Acris Antibodies
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PSKH1 - H00005681-Q01-25 from Acris Antibodies
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PSKH1 fusion protein - ag5953 from Proteintech Group
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PSKH1 fusion protein - ag6292 from Proteintech Group
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Recombinant Human PSKH1, GST-tagged - PSKH1-7016H from Creative Biomart
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PSKH1 protein-GST fusion - 009-001-T07 from Rockland Immunochemicals Inc
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PSKH1 protein-GST fusion - 009-001-T07S from Rockland Immunochemicals Inc
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PSK-H1 (M295) Peptide - BS2256P from Bioworld Technology
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Recombinant Human Serine/threonine-protein kinase H1(PSKH1) - CSB-YP018863HU CSB-EP018863HU CSB-BP018863HU CSB-MP018863HU from Cusabio
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PSKH1 Blocking Peptide - abx061211 from Abbexa
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PSKH1 Recombinant Protein Antigen - NBP2-49105PEP from Novus Biologicals
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PSKH1-Antibody-N-term-L9-Blocking-Peptide - BP7179d from Abgent, a WuXi AppTec company
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PSKH1-Antibody-C-term-Blocking-Peptide - BP7179b from Abgent, a WuXi AppTec company
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PSKH1-Antibody-N-term-C3-Blocking-Peptide - BP7179a from Abgent, a WuXi AppTec company
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PSKH1-Antibody-N-term-Blocking-Peptide - BP7235a from Abgent, a WuXi AppTec company
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PSKH1 Peptide, Human - M34GP12574H from Creative Peptides
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PSKH1 Blocking Peptide - CBP5124 from Cohesion Biosciences
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PSKH1, Recombinant Protein - MBS515199 from MyBioSource
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Serine/threonine-protein kinase H1 (PSKH1), Recombinant Protein - MBS950560 from MyBioSource
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