Gene Symbol | NOSIP |
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Entrez Gene | 51070 |
Alt Symbol | CGI-25 |
Species | Human |
Gene Type | protein-coding |
Description | nitric oxide synthase interacting protein |
Other Description | eNOS-interacting protein|nitric oxide synthase-interacting protein |
Swissprots | Q96FD2 Q9Y314 |
Accessions | EAW52501 EAW52502 EAW52503 Q9Y314 AF132959 AAD27734 AK092444 AK291535 BAF84224 AK300720 BAG62395 BC009299 AAH09299 BC010077 AAH10077 BC011249 AAH11249 BC047314 BE826708 DB470916 HQ448656 ADQ33134 XM_005258964 XP_005259021 XM_006723235 XP_006723298 XM_011527015 XP_011525317 XM_011527016 XP_011525318 XM_011527017 XP_011525319 NM_001270960 NP_001257889 NM_015953 NP_057037 |
Function | Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity. {ECO:0000269|PubMed:11149895, ECO:0000269|PubMed:15548660, ECO:0000269|PubMed:16135813}. |
Subcellular Location | Cytoplasm. Nucleus. Note=Translocates from nucleus to cytoplasm in the G2 phase of the cell cycle. |
Tissue Specificity | Expressed in heart, brain and lung. Present in endothelial cells (at protein level). {ECO:0000269|PubMed:11149895}. |
NOSIP (C-2) - sc-365363 from Santa Cruz Biotechnology
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NOSIP (FL-301) - sc-67003 from Santa Cruz Biotechnology
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NOSIP (C-3) - sc-137111 from Santa Cruz Biotechnology
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NOSIP (C-13) - sc-46423 from Santa Cruz Biotechnology
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NOSIP (K-13) - sc-46425 from Santa Cruz Biotechnology
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NOSIP (G-6) - sc-137117 from Santa Cruz Biotechnology
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NOSIP (N-17) - sc-46426 from Santa Cruz Biotechnology
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NOSIP (B-3) - sc-137118 from Santa Cruz Biotechnology
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Anti-NOSIP antibody - ab96337 from Abcam
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Anti-NOSIP antibody - ab67438 from Abcam
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Anti-NOSIP antibody - N-terminal - ab173275 from Abcam
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Anti-NOSIP Antibody (aa67-95, AP) - LS-C238105 from LifeSpan Bioscience
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Anti-NOSIP Antibody (aa67-95, APC) - LS-C238106 from LifeSpan Bioscience
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Anti-NOSIP Antibody (aa67-95, Biotin) - LS-C238107 from LifeSpan Bioscience
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Anti-NOSIP Antibody (aa67-95, FITC) - LS-C238108 from LifeSpan Bioscience
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Anti-NOSIP Antibody (aa67-95, PE) - LS-C238109 from LifeSpan Bioscience
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Anti-NOSIP Antibody (aa67-95, Azide-free, HRP) - LS-C248934 from LifeSpan Bioscience
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Anti-NOSIP Antibody (aa62-295, Biotin) - LS-C298743 from LifeSpan Bioscience
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Anti-NOSIP Antibody (aa62-295, FITC) - LS-C302381 from LifeSpan Bioscience
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Anti-NOSIP Antibody (aa66-95) - LS-C323394 from LifeSpan Bioscience
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Anti-NOSIP Antibody (aa35-84) - LS-C108078 from LifeSpan Bioscience
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Anti-NOSIP Antibody (C-Terminus) - LS-C135409 from LifeSpan Bioscience
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Anti-NOSIP Antibody (aa90-184) - LS-C186243 from LifeSpan Bioscience
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Anti-NOSIP Antibody (aa62-295) - LS-C295645 from LifeSpan Bioscience
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Anti-NOSIP Antibody (aa67-95) - LS-C158408 from LifeSpan Bioscience
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