| Gene Symbol |
AP5Z1
|
| Entrez Gene |
9907
|
| Alt Symbol |
KIAA0415, SPG48, zeta
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
adaptor-related protein complex 5, zeta 1 subunit
|
| Other Description |
AP-5 complex subunit zeta-1|adapter-related protein complex 5 zeta subunit|adaptor-related protein complex 5 zeta subunit|zeta5
|
| Swissprots |
Q8N3X2 O43299 Q96H80
|
| Accessions |
EAL23965 EAW87294 EAW87295 EAW87296 EAW87297 EAW87298 EAW87299 O43299 AB007875 BAA24845 AK092068 BC008841 AAH08841 BC014240 BC037399 AAH37399 BI766915 BQ228738 CD671081 XR_242109 NM_014855 NP_055670
|
| Function |
As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:20613862 it is a putative helicase required for efficient homologous recombination DNA double-strand break repair. {ECO:0000269|PubMed:20613862, ECO:0000269|PubMed:22022230}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:20613862}. Nucleus {ECO:0000269|PubMed:20613862}. Note=By SDS-PAGE, 2 isoforms have been observed, the shorter seems to be predominantly nuclear and the longer is mostly cytoplasmic. {ECO:0000269|PubMed:20613862}.
|