Gene Symbol | AP5Z1 |
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Entrez Gene | 9907 |
Alt Symbol | KIAA0415, SPG48, zeta |
Species | Human |
Gene Type | protein-coding |
Description | adaptor-related protein complex 5, zeta 1 subunit |
Other Description | AP-5 complex subunit zeta-1|adapter-related protein complex 5 zeta subunit|adaptor-related protein complex 5 zeta subunit|zeta5 |
Swissprots | Q8N3X2 O43299 Q96H80 |
Accessions | EAL23965 EAW87294 EAW87295 EAW87296 EAW87297 EAW87298 EAW87299 O43299 AB007875 BAA24845 AK092068 BC008841 AAH08841 BC014240 BC037399 AAH37399 BI766915 BQ228738 CD671081 XR_242109 NM_014855 NP_055670 |
Function | As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:20613862 it is a putative helicase required for efficient homologous recombination DNA double-strand break repair. {ECO:0000269|PubMed:20613862, ECO:0000269|PubMed:22022230}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:20613862}. Nucleus {ECO:0000269|PubMed:20613862}. Note=By SDS-PAGE, 2 isoforms have been observed, the shorter seems to be predominantly nuclear and the longer is mostly cytoplasmic. {ECO:0000269|PubMed:20613862}. |
KIAA0415 CRISPR/Cas9 KO Plasmid (h) - sc-405666 from Santa Cruz Biotechnology
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KIAA0415 HDR Plasmid (h) - sc-405666-HDR from Santa Cruz Biotechnology
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KIAA0415 Double Nickase Plasmid (h) - sc-405666-NIC from Santa Cruz Biotechnology
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KIAA0415 Double Nickase Plasmid (h2) - sc-405666-NIC-2 from Santa Cruz Biotechnology
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KIAA0415 CRISPR Activation Plasmid (h) - sc-405666-ACT from Santa Cruz Biotechnology
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KIAA0415 CRISPR Activation Plasmid (h2) - sc-405666-ACT-2 from Santa Cruz Biotechnology
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KIAA0415 Lentiviral Activation Particles (h) - sc-405666-LAC from Santa Cruz Biotechnology
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KIAA0415 Lentiviral Activation Particles (h2) - sc-405666-LAC-2 from Santa Cruz Biotechnology
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KIAA0415 siRNA (h) - sc-89435 from Santa Cruz Biotechnology
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KIAA0415 shRNA Plasmid (h) - sc-89435-SH from Santa Cruz Biotechnology
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KIAA0415 shRNA (h) Lentiviral Particles - sc-89435-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU141251 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11077 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11077 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03454 from Sigma-Aldrich
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AP5Z1 siRNA (Human) - CRH6652 from Cohesion Biosciences
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AP5Z1 - MBS8221561 from MyBioSource
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shRNA set against Human KIAA0415 (NM_014855.2) - SHH324559 from Creative biogene
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Human AP5Z1 siRNA - orb267154 from Biorbyt
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AP5Z1 shRNA Plasmid (Human) - CHH6652 from Cohesion Biosciences
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AP5Z1 miRNA 3'UTR clone - MiUTR3H-12995 from Creative biogene
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