AP5Z1

Gene Symbol AP5Z1
Entrez Gene 9907
Alt Symbol KIAA0415, SPG48, zeta
Species Human
Gene Type protein-coding
Description adaptor-related protein complex 5, zeta 1 subunit
Other Description AP-5 complex subunit zeta-1|adapter-related protein complex 5 zeta subunit|adaptor-related protein complex 5 zeta subunit|zeta5
Swissprots Q8N3X2 O43299 Q96H80
Accessions EAL23965 EAW87294 EAW87295 EAW87296 EAW87297 EAW87298 EAW87299 O43299 AB007875 BAA24845 AK092068 BC008841 AAH08841 BC014240 BC037399 AAH37399 BI766915 BQ228738 CD671081 XR_242109 NM_014855 NP_055670
Function As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:20613862 it is a putative helicase required for efficient homologous recombination DNA double-strand break repair. {ECO:0000269|PubMed:20613862, ECO:0000269|PubMed:22022230}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:20613862}. Nucleus {ECO:0000269|PubMed:20613862}. Note=By SDS-PAGE, 2 isoforms have been observed, the shorter seems to be predominantly nuclear and the longer is mostly cytoplasmic. {ECO:0000269|PubMed:20613862}.

Human SPG48 full length protein - ab160708 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160708 on a 12.5% SDS-PAGE stained with Coomassie Blue.

AP5Z1 Antibody Blocking Peptide - LS-E7787 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human KIAA0415 Protein - H00009907-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

K0415-Antibody-Center-Blocking-peptide - BP5236c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

KIAA0415 - H00009907-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

KIAA0415 - H00009907-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

Recombinant Human AP5Z1, His-tagged - AP5Z1-3545H from Creative Biomart

Category Protein
Source E. Coli or Yeast
Species Human

Recombinant Human AP5Z1 - AP5Z1-1196H from Creative Biomart

Category Protein
Source Mammalian Cells
Species Human

Recombinant Human AP-5 complex subunit zeta-1(AP5Z1) ,partial - CSB-YP012190HU CSB-EP012190HU CSB-BP012190HU CSB-MP012190HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

AP-5 complex subunit zeta-1(AP5Z1) ,partial, Recombinant Protein - MBS1189640 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

KIAA0415 Protein - NBP1-92049PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

PKC iota/zeta Blocking Peptide - abx061644 from Abbexa

Category Peptide

AP5Z1 Peptide, Human - M34GP00736H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

KIAA0415 fusion protein - Ag26961 from Proteintech Group

Category Protein
Source E. coli -derived, PET28a
Species Human
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